FEATURES INTESTINAL ACTINOMYCOSIS
Abstract
The results of the single-center study of the intestinal actinomycosis patients, treated at the Research Institute of mycological clinic in 2005-2016. Age of patients from 8 to 81 year, median - 42 (36,5÷52). Risk factors for intestinal actinomycosis were acute appendicitis with perforation (OR= 3.857[1.527-28.242]). Appendix (64 %), omentum (64 %) are the most common abdominal sites of actinomycosis. Patients may present with non-specific symptoms such as fever (100 %), abdominal pain (91 %), weight loss (36 %). The formation of spontaneous draining of purulent material was in 27 % cases. The time from onset to diagnosis varied from a few weeks to two years (median - 27 +/- 2 days). Surgical resection of infected tissue and long-term antibiotic therapy will be effective in the treatment of abdominal actinomycosis - 94 %
About the Authors
O. P. Kozlova
I. Metchnikov North-West State Medical University
Russian Federation
Russian Federation
M. A. Sheviakov
I. Metchnikov North-West State Medical University
Russian Federation
Russian Federation
N. N. Klimko
I. Metchnikov North-West State Medical University
Russian Federation
Russian Federation
References
1. Weese WC, Smith IM. A study of 57 cases of actinomycosis over a 36-year period. A diagnostic ‘failure’ with good prognosis after treatment. Arch Intern Med. 1975, vol. 135, pp. 1562-1568.
2. Deshmukh N., Heaney S. J. Actinomycosis at multiple colonic sites. Am J Gastroenterol, 1986, vol. 81, pp. 1212-1214
3. Lee C. M., Ng S. H., Wan Y. L., et al. Gastric actinomycosis. J Formos Med Assoc. 1996, vol. 95, pp. 66-68
4. Lee I.-J., Ha H. K., Park C. M., et al. Abdominopelvic actinomycosis involving the gastrointestinal tract: CT features. Radiology. 2001, vol. 220, pp.76-80
5. Harsch I. A., Benninger J., Niedobitek G., et al. Abdominal actinomycosis: complication of endoscopic stenting in chronic pancreatitis. Endoscopy. 2001, vol. 33, pp.1065-1069
6. Sharma M., Briski L. E., Khatib R.et al. Hepatic actinomycosis: an overview of salient features and outcome of therapy. Scand J Infect Dis. 2002, vol. 34, pp. 386-391
7. Kodali U, Mallavarapu R, Goldberg MJ. Abdominal actinomycosis presenting as lower gastrointestinal bleeding. Endoscopy. 2003, vol. 35, pp. 451-453
8. Wagenlehner FM, Mohren B, Naber KG, Männl HF. Abdominal actinomycosis. Clin Microbiol Infect. 2003, vol. 9, pp. 881-885
9. Fazeli MS, H Bateni H. Actinomycosis: a rare soft tissue infection. Dermatol Online J. 2005, vol. 11(3), pp.18
10. Hefny A. F., Joshi S., Saadeldin Y. A., et al. Primary anterior abdominal wall actinomycosis. Singapore Med J. 2006, vol. 47, pp.419-421
11. Garner J. P., Macdonald M., Kumar P. K. Abdominal actinomycosis. International Journal of Surgery. 2007, vol. 5, pp. 441-448
12. Gerda Trutnovsky, Karl Tamussino, and Olaf Reich Short-term antibiotic treatment of pelvic actinomycosis. International Journal of Gynecology & Obstetrics. 2008, vol. 101, pp. 203-204
13. Choi MM, Baek JH, Lee JN, Park S, Lee WS Clinical Features of Abdominopelvic Actinomycosis: Report of Twenty Cases and Literature Review. Yonsei Med J. 2009, vol. 50(4), pp. 555-559
14. Privitera A, Milkhu CS, Datta V, Rodriguez-Justo M, Windsor A, Cohen CR. Actinomycosis of the sigmoid colon: A case report. World J Gastrointest Surg. 2009, vol. 1(1), pp. 62-64.
15. Климко Н. Н. Микозы: диагностика и лечение. СПб., 2009, C.308-313
16. Козлова О. П., Мирзабалаева А. К., Чернопятова Р. М., Цинзерлинг В. А., Амбалова Ф. Ю., Сергеева И. В., Горгиджанян Р. С., Климко Н. Н. Случай успешного лечения распространенной формы абдоминального актиномикоза. Инфектология. 2009, Т. 1, № 2/3, С. 81-86
17. Yu CY, Chang WC, Gao HW, Chao TY, Huang GS, Hsieh CB. Metastatic hepatic actinomycosis. Am J Med. 2010, vol. 123, pp. 9-11
18. Paola Acquaro, Fulvio Tagliabue, Gianmaria Confalonieri, Paolo Faccioli. Abdominal wall actinomycosis simulating a malignant neoplasm: Case report and review of the literature World J Gastrointest Surg. 2010, vol. 2(7), pp. 247-250
19. Valour F, Sénéchal A, Dupieux C, et al. Actinomycosis: Etiology, clinical features, diagnosis, treatment, and management. Infect Drug Resist. 2014, vol. 7, pp. 183-197
20. Russo TA. Agents of actinomycosis. In: Bennett JE, Dolin R, Blaser MJ, editors. Mandell, Douglas and Bennett’s principles and practice of infectious diseases. 8th ed. Philadelphia, PA: Elsevier Saunders. 2015, pp. 3864-3873
21. Eenhuis LL, de Lange ME, Samson AD, Busch OR. Spontaneous Bacterial Peritonitis due to Actinomyces Mimicking a Perforation of the Proximal Jejunum. Am J Case Rep. 2016, vol. 17, pp. 616-620.
Review
For citations:
Kozlova O.P., Sheviakov M.A., Klimko N.N. FEATURES INTESTINAL ACTINOMYCOSIS. Experimental and Clinical Gastroenterology. 2017;(11):55-59. (In Russ.)
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