THE INFLUENCE OF CHRONIC PANCREATITIS ON THE TYPE OF REFLUX AND ENDOSCOPIC PICTURE OF DISTAL ESOPHAGUS
Abstract
The purpose of the study. To compare the type of reflux and endoscopic pattern of distal esophagus of patients with a combination of GERD-chronic pancreatitis and monopathology of GERD. Materials and methods: 155 patients with GERD were examined. The first group consisted of 75 patients with a combination of GERD and chronic pancreatitis, the second with 80 patients with monopathology. The analysis was applied to the data of fibroesophagogastroduodenoscopy with biopsy, daily 24-hour pH-metry of the esophagus and the stomach, multispiral computed tomography of the abdomen. Results. The combination of GERD and chronic pancreatitis increases the likelihood of reflux with pH >7 and independently on the type of reflux worsen clearance of the esophagus, characterizing by a higher frequency of erosive esophagitis and Barrett’s esophagus.
About the Authors
N. A. Kozlova
Non-state healthcare institution «Road clinical hospital at the station Irkutsk-Passenger JSC ”Russian Railways”»
Russian Federation
Russian Federation
E. V. Onuchina
Irkutsk State Medical Academy of Postgraduate Education - Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education «Russian Medical Academy of Continuing Professional Education» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
V. A. Markelova
Non-state healthcare institution «Road clinical hospital at the station Irkutsk-Passenger JSC ”Russian Railways”»
Russian Federation
Russian Federation
I. V. Temnikova
Non-state healthcare institution «Road clinical hospital at the station Irkutsk-Passenger JSC ”Russian Railways”»
Russian Federation
Russian Federation
References
1. El-Serag HB, Sweet S, Winchester CC, Dent J. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 2014.-№ 63(6). - Р.871-800.
2. Löhr J. M., Dominguez-Munoz E., Rosendahl J. et al. United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis (HaPanEU). United European Gastroenterol J. 2017. - № 5(2). - Р.153-199.
3. Васильев Ю. В., Машарова А. А., Янова О. Б. Гастроэзофагеальная рефлюксная болезнь, сочетающаяся с хроническим панкреатитом и язвенной болезнью. Материалы 6-й Вост.-Сиб. гастроэнтерологической конференции «Клинико-эпидемиологические и этно-экологические проблемы заболеваний органов пищеварения». - Красноярск. 2005. - С. 18-19.
4. Губергриц Н. Б., Крюк Н. А. Особенности лечения больных хроническим панкреатитом в сочетании с гастроэзофагеальной рефлюксной болезнью. Гастроэнтерология СПб. 2007.-№ 1-2.-С. 114.
5. Горбань В. В., Каруна Ю. В., Горбань Е. В. Клиническое значение эндоскопической манометрографии верхнего отдела желудочно-кишечного тракта у больных хроническим панкреатитом Экспериментальная и клиническая гастроэнтерология. 2015.-№ 10. - С.18-23.
6. Машарова А. А., Бордин Д. С. Особенности гастоэзофагеальной рефлюксной болезни у пожилых. Экспериментальная и клиническая гастроэнтерология. 2007. - № 4.-С. 37-40.
7. Онучина Е. В., Цуканов В. В. Проспективное пятилетнее наблюдение ГЭРБ у лиц пожилого и старческого возраста. Клин. геронтология. 2010.-№ 1-2.-С.34-38.
8. Vakil N., van Zanden S. V., Kahrilas P. et al. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am. J. Gastroenterol. 2006.-№ 101 (8).-Р. 1900-1920.
9. Lundell L. R., Dent J., Bennet J. R. Endoscopic assessment of oesophagitis clinical and functional correlates and further validation of Los Angeles classification. Gut. 1999.-№ 45.-Р.72-180.
10. Spechler S. J., Sharma P., Souza R. F. et al. American Gastroenterological Association medical position statement on the management of Barrett’s esophagus. Gastroenterology 2011.-№ 140.-Р. 1084-91.
11. Shaheen N. J., Falk G. W., Iyer P. G., et al. ACG Clinical Guideline: Diagnosis and Management of Barrett’s Esophagus. Am J Gastroenterol 2016.-№ 111.-Р. 30-50.
12. Ивашкин В. Т. с соавт. Рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению хронического панкреатита РЖГГК. 2014.-№ 46.-С.70-97.
Review
For citations:
Kozlova N.A., Onuchina E.V., Markelova V.A., Temnikova I.V. THE INFLUENCE OF CHRONIC PANCREATITIS ON THE TYPE OF REFLUX AND ENDOSCOPIC PICTURE OF DISTAL ESOPHAGUS. Experimental and Clinical Gastroenterology. 2017;(11):31-33. (In Russ.)
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