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ENDOSCOPIC AND MORPHOLOGICAL DESCRIPTION OF THE GASTROINTESTINAL TRACT PROXIMAL PART AFFECTIONS AGAINST THE BACKGROUND OF ANTIPLATELET DRUGS

Abstract

The aim of the work is to estimate endoscopic and morphological peculiarities of the gastrointestinal tract proximal part against the background of acetylsalicilic acid intake, the acetylsalicilic acid in combination with clopidogrel and acetylsalicilic acid in combination with ticagrelor. Materials and methods. There were examined 65 patients taking the different variants of antiplatelet therapy. Data on fibroesophagogastroduodenoscopy and biopsy material were analyzed. Results. In the proximal parts of the gastrointestinal tract, various variants of antiplatelet therapy showed no endoscopic and morphological differences in the changes in the mucous tunic of the stomach and duodenum. In the group of patients taking acetylsalicylic acid and clopidogrel, esophagitis of varying severity, hyperplasia of basal layer, elongation of papillae and greatest polymorphocellular infiltration appeared to be more often.

About the Authors

D. A. Strezhneva
Irkutsk State Medical Academy of Postgraduate Education - Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education «Russian Medical Academy of Continuing Professional Education» of the Ministry of Healthcare of the Russian Federation
Russian Federation


E. V. Onuchina
Irkutsk State Medical Academy of Postgraduate Education - Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education «Russian Medical Academy of Continuing Professional Education» of the Ministry of Healthcare of the Russian Federation
Russian Federation


A. Yu. Sisenkova
Irkutsk Pathoanatomical Bureau
Russian Federation


References

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Review

For citations:


Strezhneva D.A., Onuchina E.V., Sisenkova A.Yu. ENDOSCOPIC AND MORPHOLOGICAL DESCRIPTION OF THE GASTROINTESTINAL TRACT PROXIMAL PART AFFECTIONS AGAINST THE BACKGROUND OF ANTIPLATELET DRUGS. Experimental and Clinical Gastroenterology. 2017;(11):22-24. (In Russ.)

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ISSN 1682-8658 (Print)