EFFECTIVENESS OF MAXIMUM EARLY VISUALIZATION FOR ESTIMATION PANCREATIC GLAND’S AFFECTION VOLUME AT NECROTIZING PANCREATITIS

Abstract

Research aim to estimate possibility of maximum early visualization of pathological focus at pancreatic gland by the use CT angiography with Bolus tracking. Materials and methods: 30 patients, who were admitted to this hospital before 72 hours from the begin of disease, with severe necrotizing acute pancreatitis Maximum early visualization was made after 72 hours from the begin of disease on multispiral 4 multislice tomograph «Lightspeed», with program Bolus tracking. We estimateв volume of perfusion’s disorder of pancreatic glandular tissue. For finale estimation of formed necrotic affection we repeated CT at the third week of disease. Results: 2 (6,67 %) patients hadn’t signs of perfusion’s disorder of pancreatic glandular tissue. 15 (50,00 %) patients had perfusion’s disorder volume less than 30 % of pancreatic gland’s volume. 8 (26,67 %) patients had perfusion’s disorder volume from 30 % to 50 %, 4 (13,33 %) patients had perfusion’s disorder volume from 50 % to 75 % and 1 patients had perfusion’s disorder volume more than 75 %. At the third week of disease patients, who hadn’t signs of perfusion’s disorder, hadn’t signs of pancreatonecrosis. 17 (56,67 %) patients had small-focal pancreatonecrosis, 7 (23,33 %) patients had large-focal pancreatonecrosis, 3 (10 %) patients had subtotal pancreatonecrosis. Affection more than 75 % of pancreatic gland’s volume also was confirmed. Sensitivity of estimation of perfusion’s disorder for prognostication of necrotizing affection of pancreatic gland was 100 %, specificity 33,33 %, accuracy - 100 %, positive and negative predictive value - 87,50 % and 100 %, AUC - 0,944.