FEATURES OF NUTRITIONAL STATUS IN PATIENTS WITH ARTERIAL HYPERTENSION IN COMBINATION WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Abstract

The state of nutritional status was studied in 161 patients with arterial hypertension (AH) in combination with chronic obstructive pulmonary disease (COPD), divided in three groups: 1st (54) - with AH, 2nd (52) - with COPD, 3rd (55) - with AH in combination with COPD. Based on the assessment of actual nutrition, anthropometric survey data, lipid, protein and carbohydrate metabolism, the level of adipokines and cytokines, it was determined that the nutritional features of patients with AH in combination with COPD are: high values of the index waist circumference / circumference of hips, increased fat mass and extracellular fluid, decrease in muscle component of the body, increased levels of total cholesterol and its atherogenic fractions, reducing the concentration of prealbumin, increased levels of leptin and resistin on the background of decreased adiponectin and leptin-binding receptor and increasing concentrations of the studied cytokines IL-1, IL-6, IL-18 and TNF-α. It was found that patients with AH in combination with COPD index waist circumference / circumference of hips for assessment of nutritional status has a greater diagnostic value than body mass index. Timely detection and correction of nutritional disorders will improve the effectiveness of treatment of patients.