DISTURBANCE OF GASTRIC MOTILITY IN PATIENTS WITH THE OVERLAP SYNDROME OF THE OF GASTROESOPHAGEAL REFLUX DISEASE AND FUNCTIONAL DYSPEPSIA
Abstract
The aim of this study was to investigate the motility of the stomach through the study of myoelectric activity in patients with the overlap syndrome of the gastroesophageal reflux disease and functional dyspepsia. Sixty-two patients with the overlap syndrome of the of gastroesophageal reflux disease and functional dyspepsia were examined. The control group consisted of 46 healthy volunteers. The diagnosis of the overlap syndrome of the of gastroesophageal reflux disease and functional dyspepsia was established on symptoms, data of esophagogastroduodenoscopy, 24-hour pH-meter or 24-hour impedance-pH-metry, Roman criteria III. Myoelectric activity of the stomach (MAS) was assessed by 24-hour electrogastrography (EGG) on an empty stomach and after taking a standard test breakfast (430 kcal, Nutri Drink). In preprandial and postprandial periods of detection of MAS, motility disorders were detected: a decrease in the dominant frequency of slow stomach waves, an increase in the coefficient of its instability. Chronotropic MAS dysfunction was characterized by a decrease in normogastric activity, an increase in bradygastric and tachigastric activities. Food intake led to a partial correction of MAS: an increase in normogastry and a decrease in bradygastria. The revealed disturbances are one of the mechanisms of the development of gastric motility disorders that cause the development of the overlap syndrome of the gastroesophageal reflux disease and functional dyspepsia.
About the Authors
V. D. Pasechnikov
Federal State Government-financed Educational Institution of Higher Education “Stavropol State Medical University”
Russian Federation
Russian Federation
I. V. Golub
Federal State Government-financed Educational Institution of Higher Education “Stavropol State Medical University”
Russian Federation
Russian Federation
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Review
For citations:
Pasechnikov V.D., Golub I.V. DISTURBANCE OF GASTRIC MOTILITY IN PATIENTS WITH THE OVERLAP SYNDROME OF THE OF GASTROESOPHAGEAL REFLUX DISEASE AND FUNCTIONAL DYSPEPSIA. Experimental and Clinical Gastroenterology. 2017;(7):54-57. (In Russ.)
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