ГАСТРОЭЗОФАГЕАЛЬНАЯ РЕФЛЮКСНАЯ БОЛЕЗНЬ И ИНФЕКЦИЯ HELICOBACTER PYLORI
Аннотация
Ассоциация между гастроэзофагеальной рефлюксной болезнью (ГЭРБ) и инфекцией Helicobacter pylori (H. pylori) является поводом для дискуссий уже в течение многих лет. Многочисленные исследования и метаанализы, проведенные к настоящему времени, продемонстрировали обратную корреляцию инфекции H. pylori (особенно CagA-положительных штаммов) с развитием осложненных форм ГЭРБ, включая пищевод Баррета и аденокарциному пищевода. Предположительно, развитие H. pylori-ассоциированного атрофического пангастрита способно оказывать протективную функцию, снижая аномальное воздействие соляной кислоты на слизистую оболочку дистального отдела пищевод. Согласно нескольким метаанализам успешная эрадикация H. pylori является фактором риска развития ГЭРБ в азиатской популяции, но не оказывает достоверного влияния у населения западных стран.
Об авторах
Д. Н. Андреев
ФГБОУ ВО «Московский государственный медико-стоматологический университет имени А. И. Евдокимова» Минздрава России
Россия
Россия
И. В. Маев
ФГБОУ ВО «Московский государственный медико-стоматологический университет имени А. И. Евдокимова» Минздрава России
Россия
Россия
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Рецензия
Для цитирования:
Андреев Д.Н., Маев И.В. ГАСТРОЭЗОФАГЕАЛЬНАЯ РЕФЛЮКСНАЯ БОЛЕЗНЬ И ИНФЕКЦИЯ HELICOBACTER PYLORI. Экспериментальная и клиническая гастроэнтерология. 2017;(6):105-111.
For citation:
Andreev D.N., Maev I.V. GASTROESOPHAGEAL REFL UX DISEASE AND INFECTION HELICOBACTER PYLORI. Experimental and Clinical Gastroenterology. 2017;(6):105-111. (In Russ.)
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