ASSESSMENT OF THE INTESTINAL PERMEABILITY IN PATIENTS WITH AUTOIMMUNE HEPATITIS AND OVERLAP SYNDROME
Abstract
The article presented complex assessment of intestinal permeability in patients with autoimmune hepatitis (AIH) and overlap syndrome (OS). The study included 82 people: 26 patients with AIH, 26 - with OS and 30 healthy controls. All included into the study underwent a triple sugar test. There was increasing of small intestinal permeability in patients with AIH 0,11 [0,075; 0,18] (p<0,001) and OS 0,2 [0,088; 0,3] (p<0,001), comparing with control group 0,013 [0,01; 0,025]. In patients with cirrhosis, portal hypertension and liver failure intestinal permeability changes were more prominent - increasing small bowel and colonic permeability.
About the Authors
D. R. Akberova
Kazan State Medical University
Russian Federation
Russian Federation
S. A. Koshkin
Kazan Federal University
Russian Federation
Russian Federation
A. H. Odintsova
Republican Clinical Hospital
Russian Federation
Russian Federation
D. I. Abdulganieva
Kazan State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Akberova D.R., Koshkin S.A., Odintsova A.H., Abdulganieva D.I. ASSESSMENT OF THE INTESTINAL PERMEABILITY IN PATIENTS WITH AUTOIMMUNE HEPATITIS AND OVERLAP SYNDROME. Experimental and Clinical Gastroenterology. 2017;(6):44-47. (In Russ.)
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