INCREASED FUNCTIONAL ACTIVITY OF APUD CELL OF THE ESOPHAGUS AND THE STOMACH AT THE GASTROESOPHAGEAL REFL UX IN THE ELDERLY
Abstract
Revealed clinical and psycho-physical manifestations, especially the pathogenesis, endoscopic and morphological pattern of mucosal pathology Gastroesophageal Zone in elderly patients with erosive and non-erosive form of gastroesophageal reflux disease. A total of 226 patients studied nosology. Applied clinical, endoscopic, morphological, immunohistochemical methods. Increasing the number and functional activity of the stomach and esophagus APUD cell producing nitric oxide synthase and endothelin-1 in patients in comparison with comparison groups, suggests their main pathogenic factor of the disease. Cell hyperplasia cells secreting nitric oxide synthase and endothelin-1, more than twice, there is the formation of refractory form of the disease.
About the Authors
A. A. Svistunov
I. M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
M. A. Osadchuk
I. M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
N. V. Kireyeva
I. M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
S. N. Nikolenko
I. M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
A. E. Lazareva
I. M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Svistunov A.A., Osadchuk M.A., Kireyeva N.V., Nikolenko S.N., Lazareva A.E. INCREASED FUNCTIONAL ACTIVITY OF APUD CELL OF THE ESOPHAGUS AND THE STOMACH AT THE GASTROESOPHAGEAL REFL UX IN THE ELDERLY. Experimental and Clinical Gastroenterology. 2017;(2):67-70. (In Russ.)
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