THE INFLUENCE OF GASTRINEMIA ON THE CLINICAL COURSE OF ACUTE VIRAL HEPATITIS B IN CHILDREN

Abstract

The purpose of the study was the levels of blood serum gastrin in children with a mild form of viral hepatitis B and their importance in clinical manifestations of the disease. Materials and Methods of the Research. 48 children aged between 3 and 15 years old have been examined as per viral hepatitis standard testing with additional measuring of morning gastrin level. The first group included 33 children suffering from a mild form of hepatitis B. The control group (norm) consisted of 15 healthy children. Results of the Research. The majority of children (69,7%) suffering from a mild form of hepatitis B had a higher gastrin level in the blood serum as compared to the healthy children (norm). It was proved by the findings of esophagogastroduodenoscopy (EGDS) as functional dyspepsia. Conclusions 1. Icteric hepatitis B in children starting with mild forms of the disease is in most cases accompanied by functional dyspepsia. 2. Icteric hepatitis B in children starting with mild forms of the disease should be treated as hepatic pathology accompanied by functional dyspepsia. It will enable to raise effectiveness of their therapy. 3. An infection disease doctor should carry out the clinical supervision and rehabilitation of children who have had icteric hepatitis B starting with mild forms of the disease together with a gastroenterologist; it will ensure the timely detection of their gastroduodenal pathology and will have a positive effect for increasing a number of healthy children.