THE CONDITION OF INTESTINAL MICROBIOCENOSIS IN PATIENTS WITH INFECTIOUS AND INFLAMMATORY COMPLICATIONS AFTER CARDIAC SURGERY

Abstract

The purpose of thе study - was to explore peculiarity of the colon’s microbiocenosis of patients with infectious and inflammatory complications occurring in the postoperative period after cardiac surgery. Materials and methods. Bacteriological examination of 89 patients with such diagnoses as sternomediastinitis, sternum’s instability, osteomyelitis of sternum and ribs was conducted. Qualitative and quantitative composition of the colon’s microflora have been studied according to the standard “Treatment Protocol. Intestinal dysbiosis”. “ Results. Dysbiotic changes of the colon’s microflora of varying severity were revealed in 96.62% of cases. They were recorded in different groups of patients with almost the same frequency. A significant decrease of concentration of anaerobic obligate symbionts, especially Bifidobacterium and Bacteroides, were found. It is against this background that the range has been greatly expanded and the number of conditionally pathogenic bacteria, especially Enterobacteriaceae, has been increased. In some patients in the intestinal biotope were also found Staphylococcus aureus and Pseudomonas aeruginosa. Conclusions. Infectious-inflammatory complications that occur after cardiac surgery are characterized by the development of dysbiosis of colon, which aggravates the disease, on the one hand. On the other hand, an excessive accumulation of opportunistic pathogens might have contributed to their translocation into the surgical wound and induced the development of these complications. All patients are required the intensive correctional comprehensive nutritional therapy after cardiac surgery.