Stem cell therapy for complex perianal fistulas in Crohn’s disease patients
https://doi.org/10.31146/1682-8658-ecg-246-2-84-88
Abstract
Perianal fistulas are a severe complication of Crohn’s disease, significantly reducing patients’ quality of life. Despite the use of immunosuppressive and biological therapy, as well as modern surgical techniques, many patients fail to achieve sustained and long-term remission. In the last decade, cell-based therapies aimed at correcting the local inflammatory response and stimulating regenerative processes have attracted the attention of researchers. This review summarizes current data on the efficacy, safety, and potential of autologous and allogeneic cell products for the treatment of perianal fistulas in Crohn’s disease.
About the Authors
Z. M. Abdulatipova
Loginov Moscow Clinical Scientific Center
Russian Federation
Russian Federation
O. V. Knyazev
Loginov Moscow Clinical Scientific Center
Russian Federation
Russian Federation
M. A. Danilov
Loginov Moscow Clinical Scientific Center
Russian Federation
Russian Federation
G. A. Krotov
Loginov Moscow Clinical Scientific Center
Russian Federation
Russian Federation
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Review
For citations:
Abdulatipova Z.M., Knyazev O.V., Danilov M.A., Krotov G.A. Stem cell therapy for complex perianal fistulas in Crohn’s disease patients. Experimental and Clinical Gastroenterology. 2026;(2):84-88. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-246-2-84-88
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