Preview

Экспериментальная и клиническая гастроэнтерология

Расширенный поиск

КИШЕЧНЫЙ БАРЬЕР, МИКРОБИОТА, МИКРОБИОМ

Полный текст:

Аннотация

В обзоре рассмотрено современное состояние таких направлений развития физиологии пищеварения, как структура и функции кишечного барьера, микробиота пищеварительного тракта в ее отношениях с макроорганизмом.

Об авторе

А. Т. Марьянович
Северо-Западный государственный медицинский университет им. И. И. Мечникова
Россия


Список литературы

1. Руш К., Петерс У. Кишечник - центр управления иммунной системы // Биологическая медицина. - 2003. - Март. - С. 4-8.

2. Antoine, J. M. Probiotics: beneficial factors of the defence system / J. M. Antoine // Proc. Nutr. Soc. - 2010. - Vol. 69, N3. - P. 429-433.

3. Assimakopoulos, S. F. Pathophysiology of increased intestinal permeability in obstructive jaundice / S. F. Assimakopoulos, C. D. Scopa, C. E. Vagianos // World J. Gastroenterol. - 2007. - Vol. 13, N48. - P. 6458-6464.

4. Bile modulates intestinal epithelial barrier function via an extracellular signal related kinase 1/2 dependent mechanism / R. Yang [et al.] // Intensive Care Med. - 2005. - Vol. 31, N5. - P. 709-717.

5. Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability / P. D. Cani [et al.] // Gut. - 2009. - Vol. 58, N8. - P. 1091-1103.

6. Collett, A. Rapid induction of P-glycoprotein expression by high permeability compounds in colonic cells in vitro: a possible source of transporter mediated drug interactions? / A. Collett, J. Tanianis-Hughes, G. Warhurst // Biochem. Pharmacol. - 2004. - Vol. 68, N4. - P. 783-790.

7. Commensal microflora induce host defense and decrease bacterial translocation in burn mice through toll-like receptor 4 / L. W. Chen [et al.] // J. Biomed. Sci. - 2010. - N17. - P. 48.

8. Conroy, M. E. Intestinal immune health / M. E. Conroy, W. A. Walker // Nestle Nutr. Workshop Ser. Pediatr. Program. - 2008. - Vol. 62. - P. 111-121.

9. Deplancke, B. Microbial modulation of innate defense: goblet cells and the intestinal mucus layer / B. Deplancke, H. R. Gaskins // Am. J. Clin. Nutr. - 2001. - Vol. 73, N6. - P. 1131S-1141S.

10. Ding, L. A. Gut in diseases: physiological elements and their clinical significance / L. A. Ding, J. S. Li // World J. Gastroenterol. - 2003. - Vol. 9, N11. - P. 2385-2389.

11. Efferent vagal nerve stimulation attenuates gut barrier injury after burn: modulation of intestinal occludin expression / T. W. Costantini [et al.] // J. Trauma. - 2010. - Vol. 68, N6. - P. 1349-1354.

12. Formyl peptide receptor-1 activation enhances intestinal epithelial cell restitution through phosphatidylinositol 3-kinase-dependent activation of Rac1 and Cdc42 / B. A. Babbin [et al.] // J. Immunol. - 2007. - Vol. 179, N12. - P. 8112-8121.

13. Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice / A. S. Lee [et al.] // Diabetologia. - 2010. - Vol. 53, N4. - P. 741-748.

14. Hansen, J. The role of mucosal immunity and host genetics in defining intestinal commensal bacteria / J. Hansen, A. Gulati, R. B. Sartor // Curr. Opin. Gastroenterol. - 2010. - Vol. 26, N6. - P. 564-571.

15. Hollande, F. Signaling the junctions in gut epithelium / F. Hollande, A. Shulkes, G. S. Baldwin // Sci. STKE. 2005. - 2005. - N. 277. - P. pe13.

16. Host-bacterial symbiosis in health and disease / J. Chow [et al.] // Adv. Immunol. - 2010. - Vol. 107. - P. 243-274.

17. Hydrophobicity of mucosal surface and its relationship to gut barrier function / X. Qin [et al.] // Shock. - 2008. - Vol. 29, N3. - P. 372-376.

18. Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice / C. Zhang [et al.] // ISME J. - 2010. - Vol. 4, N2. - P. 232-241.

19. Kelly, D. Commensal gut bacteria: mechanisms of immune modulation / D. Kelly, S. Conway, R. Aminov // Trends Immunol. - 2005. - Vol. 26, N6. - P. 326-333.

20. Lee, Y. K. Has the microbiota played a critical role in the evolution of the adaptive immune system? / Y. K. Lee, S. K. Mazmanian // Science. - 2010. - Vol. 330, N6012. - P. 1768-1773.

21. Liu, Z. Tight junctions, leaky intestines, and pediatric diseases / Z. Liu, N. Li, J. Neu // Acta Paediatr. - 2005. - Vol. 94, N4. - P. 386-393.

22. Live and heat-killed Lactobacillus rhamnosus GG: effects on proinflammatory and anti-inflammatory cytokines/chemokines in gastrostomy-fed infant rats / N. Li [et al.] // Pediatr. Res. - 2009. - Vol. 66, N2. - P. 203-207.

23. MacDonald, T. T. Bacterial regulation of intestinal immune responses / T.T. MacDonald, J. N. Gordon // Gastroenterol. Clin. North Am. - 2005. - Vol. 34, N3. - P. 401-412.

24. Magalhaes, J. G. The intestinal epithelial barrier: how to distinguish between the microbial flora and pathogens / J. G. Magalhaes, I. Tattoli, S. E. Girardin // Semin. Immunol. - 2007. - Vol. 19, N2. - P. 106-115.

25. Mai, V. Colonic bacterial flora: changing understandings in the molecular age / V. Mai, J. G. Morris // J. Nutr. - 2004. - Vol. 134, N2. - P. 459-464.

26. McCracken, V. J. The gastrointestinal ecosystem: a precarious alliance among epithelium, immunity and microbiota / V.J. McCracken, R. G. Lorenz // Cell Microbiol. - 2001. - Vol. 3, N1. - P. 1-11.

27. Mechanism of intestinal-derived fungal sepsis by gliotoxin, a fungal metabolite / J. S. Upperman [et al.] // J. Pediatr. Surg. - 2003. - Vol. 38, N6. - P. 966-970.

28. Migeotte, I. Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses / I. Migeotte, D. Communi, M. Parmentier // Cytokine Growth Factor Rev. - 2006. - Vol. 17, N6. - P. 501-519.

29. Molecular analysis of commensal host-microbial relationships in the intestine / L. V. Hooper [et al.] // Science. - 2001. - Vol. 291, N5505. - P. 881-884.

30. Mosenthal, A. C. Elemental and intravenous total parenteral nutrition diet-induced gut barrier failure is intestinal site specific and can be prevented by feeding nonfermentable fiber / A. C. Mosenthal, D. Xu, E. A. Deitch // Crit. Care Med. - 2002. - Vol. 30, N2. - 396-402.

31. Neish, A. S. Microbes in gastrointestinal health and disease / A. S. Neish // Gastroenterology. - 2009. - Vol. 136, N1. - P. 65-80.

32. Neu, J. Perinatal and neonatal manipulation of the intestinal microbiome: a note of caution / J. Neu // Nutr. Rev. - 2007. - Vol. 65, N6 (Pt. 1). - P. 282-285.

33. Neutrophil-mediated epithelial injury during transmigration: role of elastase / H. H. Ginzberg [et al.] // Am. J. Physiol. Gastrointest. Liver Physiol. - 2001. - Vol. 281, N3. - P. G705-G717.

34. Patterns and scales in gastrointestinal microbial ecology / J. G. Camp [et al.] // Gastroenterology. - 2009. - Vol. 136, N6. - P. 1989-2002.

35. Polyunsaturated fatty acids support epithelial barrier integrity and reduce IL-4 mediated permeability in vitro / L. E. Willemsen [et al.] // Eur. J. Nutr. - 2008. - Vol. 47, N4. - P. 183-191.

36. Predicting P-glycoprotein effects on oral absorption: correlation of transport in Caco-2 with drug pharmacokinetics in wild-type and mdr1a(-/-) mice in vivo / A. Collett [et al.] // Pharm. Res. - 2004. - Vol. 21, N5. - 819-826.

37. Prophylactic treatment with growth hormone improves intestinal barrier function and alleviates bacterial translocation in stressed rats / L. A. Ding [et al.] // Chin. Med. J. (Engl.). - 2004. - Vol. 117, N2. - P. 264-269.

38. Protection against early intestinal compromise by lipid-rich enteral nutrition through cholecystokinin receptors / J.J. de Haan [et al.] // Crit. Care Med. - 2010. - Vol. 38, N7. - P. 1592-1597.

39. Region-dependent modulation of intestinal permeability by drug efflux transporters: in vitro studies in mdr1a(-/-) mouse intestine / R. H. Stephens [et al.] // J. Pharmacol. Exp. Ther. - 2002. - Vol. 303, N3. - P. 1095-1101.

40. Role of nitric oxide and peroxynitrite in gut barrier failure / D. A. Potoka [et al.] // World J. Surg. - 2002. - Vol. 26, N7. - P. 806-811.

41. Saccharomyces cerevisiae strain UFMG 905 protects against bacterial translocation, preserves gut barrier integrity and stimulates the immune system in a murine intestinal obstruction model / S. V. Generoso [et al.] // Arch. Microbiol. - 2010. - Vol. 192, N6. - P. 477-484.

42. Sanz, Y. Gut microbiota and probiotics in modulation of epithelium and gut-associated lymphoid tissue function / Y. Sanz, G. De Palma // Int. Rev. Immunol. - 2009. - Vol. 28, N6. - P. 397-413.

43. Sharma, R. Molecular modulation of intestinal epithelial barrier: contribution of microbiota / R. Sharma, C. Young, J. Neu // J. Biomed. Biotechnol. - 2010. - Vol. 2010: 305879.

44. The role of bifidobacteria in gut barrier function after thermal injury in rats / Z. Wang [et al.] // J. Trauma. - 2006. - Vol. 61, N3. - P. 650-657.

45. Thompson, A. J. Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response / A. J. Thompson, S. A. Locarnini // Immunol. Cell Biol. - 2007. - Vol. 85, N6. - P. 435-445.


Для цитирования:


Марьянович А.Т. КИШЕЧНЫЙ БАРЬЕР, МИКРОБИОТА, МИКРОБИОМ. Экспериментальная и клиническая гастроэнтерология. 2016;(2):64-69.

For citation:


Mar’Yanovich A.T. THE INTESTINAL BARRIER, THE MICROBIOTA, MICROBIOME. Experimental and Clinical Gastroenterology. 2016;(2):64-69. (In Russ.)

Просмотров: 157


Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.


ISSN 1682-8658 (Print)