ЭРАДИКАЦИОННАЯ ТЕРАПИЯ HELICOBACTER PYLORI: НАСТОЯЩЕЕ И БУДУЩЕЕ

В последние годы частота успешной эрадикации H. рylori при применении существующих схем лечения продолжает снижаться, что объясняется в первую очередь появлением антибиотико-резистентных штаммов микроорганизма. Результаты последних исследований подтверждают факт, что стандартная тройная терапия становится неэффективным методом эрадикации H. pylori в связи с увеличением количества резистентных штаммов H.pylori. Уровень резистентности H. pylori к антибактериальным препаратам отличается как в разных странах, так в отдельных регионах в пределах одной страны. Таким образом, становится актуальным проведение исследований по изучению региональных особенностей устойчивости H. pylori к определенным антибактериальным препаратам с последующей разработкой схем эрадикационной терапии, эффективных в том или ином регионе. По-прежнему остается эффективной квадротерапия с препаратом висмута, позволяющая достичь хороших результатов. За последние годы было предложено несколько альтернативных схем эрадикации H. pylori, таких как последовательная, сопутствующая, гибридная терапии, включающих в себя три антибактериальных агента. В настоящее время эти схемы позволяют достичь хороших результатов при проведении эрадикации H. pylori.

эрадикационная терапия, антибиотикорезистентность, стандартная тройная терапия, квадротерапия с препаратом висмута, последовательная терапия, сопутствующая терапия, гибридная схема, адъювантная терапия

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