ADENOMA OF THE STOMACH: RETROSPECTIVE ANALYSIS OF ENDOSCOPIC BIOPSY MATERIAL

Abstract

The introduction of a screening diagnosis of precancerous lesions of gastric mucosa and elaboration of new methods of radical treatment is an important aspect of gastric cancer prevention. Digestive endoscopy with subsequent morphological study allows with high probability to correctly assess the structure of the lesion and to identify changes that have prognostic value. Gastric adenoma is the obligate precancerous lesion because the presence of intraepithelial neoplasia. Aim - retrospective review the clinical-morphologic characteristics and frequency of gastric adenoma in a large series of endoscopies from patients with gastric polyps. Methods - 163 gastric adenomas were diagnosed by histological examination in a series of 990 patients who had upper digestive endoscopies done. The patients were analyzed as the age, sex, and the adenomas as the histological and Yamada classification, as well as their location, size, histopathological findings studied. Results - gastric adenomas were diagnosed in 16,5% in a series of patients with gasric polyps, more frequently in the women. Gastric adenomas were primarily single and developed in the antrum of stomach. High grade dysplastic foci were found in 0,6% adenomas, which size was lesser than 2 cm. Intestinal metaplasia with high grade prognostic value was found in 18,4% cases. A carcinoma was not detected.