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Experimental and Clinical Gastroenterology

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Combination therapy of gastroesophageal reflux disease in comorbidity with functional dyspepsia

https://doi.org/10.31146/1682-8658-ecg-228-8-158-162

Abstract

It has been shown that in patients with GERD and functional dyspepsia, the use of proton pump inhibitors leads to a decrease in heartburn and pain behind the sternum. However, symptoms such as regurgitation, belching, feeling of early satiety and heaviness after eating were stopped ineffectively. The inclusion in the treatment complex of the prokinetic domperidone at a dose of 10 mg 3 times a day contributed to a more effective regression of symptoms of impaired motility of the esophagus and stomach.

About the Authors

M. M. Karimov
Republican Specialized Scientific and Practical Medical Center for Therapy and Medical Rehabilitation
Russian Federation


P. S. Zufarov
Tashkent Medical Academy
Russian Federation


G. N. Sobirova
Tashkent Medical Academy
Russian Federation


M. T. Rustamova
Tashkent Medical Academy
Russian Federation


D. K. Karimova
Republican Specialized Scientific and Practical Medical Center for Therapy and Medical Rehabilitation
Russian Federation


S. S. Khairullaeva
Tashkent Medical Academy
Russian Federation


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Review

For citations:


Karimov M.M., Zufarov P.S., Sobirova G.N., Rustamova M.T., Karimova D.K., Khairullaeva S.S. Combination therapy of gastroesophageal reflux disease in comorbidity with functional dyspepsia. Experimental and Clinical Gastroenterology. 2024;(8):158-162. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-228-8-158-162

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