Influence of nutrition and epigenetics on the development of neurodegenerative diseases in elderly and old people

Due to the growing number of elderly and senile people in the world population, there is an increase in the prevalence of neurodegenerative diseases. Alzheimer’s, Parkinson’s, multiple sclerosis, amyotrophic lateral sclerosis are the most common nosologies in this group, which are based on neuronal damage and subsequent death of the corresponding parts of the brain and spinal cord. These patients are characterized by a growing deficit in daily activities, a decrease in the productivity of cognitive functions, followed by the need for constant and long-term care, which is associated with huge economic and social costs to society. At the same time, there are no effective programs for the prevention and treatment of these diseases. In the review of the literature, the authors analyzed the works devoted to neurodegenerative diseases, the role of nutrition, epigenetics as factors in the prevention and slowing down the progression of neurodegeneration processes.

neurodegenerative diseases, Alzheimer’s disease, frailty, metabolism, epigenetics, genetics, intestinal microbiota, nutrition, ageing

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