Features of Cytomegalovirus Hepatitis in a Child with a Complicated Medical History
https://doi.org/10.31146/1682-8658-ecg-226-6-233-239
Abstract
Objective: To examine a clinical case of congenital cytomegalovirus (CMV) infection with subsequent hepatitis development in a child with a complicated medical history. Materials and Methods: The study was based on the analysis of modern literature devoted to the problem of cytomegalovirus infection in pregnant women and newborns in Russian and English, as well as the case history of a child with intrauterine cytomegalovirus infection. Results: The article presents a clinical case of a child infected with CMV, complicated by cholestasis syndrome. The child was born into a family with a history of multiple maternal diseases, premature births, and multiple complications during pregnancy. The research results indicated the presence of CMV and changes in blood biochemical parameters characteristic of cholestatic hepatitis. Therapy led to an improvement in the condition, followed by a relapse after discharge from the hospital, associated with the features of the course of CMV hepatitis in a child with a complicated obstetric and gynecological history of the mother, prematurity, and neonatal period pathology. Conclusion: The article emphasizes the difficulties of diagnosing and treating congenital CMV infection and its associated hepatological complications, as well as the need for long-term monitoring for patients with a complicated medical history.
About the Authors
I. V. Sadovnikova
Privolzhsky Research Medical University
Russian Federation
Russian Federation
V. S. Rogozhin
Privolzhsky Research Medical University
Russian Federation
Russian Federation
E. S. Belyakova
Research Clinical Institute of Childhood, Ministry of Health of the Moscow Region
Russian Federation
Russian Federation
M. . Zencheko
Research Clinical Institute of Childhood, Ministry of Health of the Moscow Region
Russian Federation
Russian Federation
A. I. Khavkin
Research Clinical Institute of Childhood, Ministry of Health of the Moscow Region
Russian Federation
Russian Federation
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For citations:
Sadovnikova I.V., Rogozhin V.S., Belyakova E.S., Zencheko M., Khavkin A.I. Features of Cytomegalovirus Hepatitis in a Child with a Complicated Medical History. Experimental and Clinical Gastroenterology. 2024;(6):233-239. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-226-6-233-239
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