The current state of the problem of intestinal microbiota according to pediatricians
https://doi.org/10.31146/1682-8658-ecg-226-6-176-187
Abstract
The mechanisms of formation of the intestinal microbiota, its influence on the health of the child, participation in physiological and pathological processes are considered. Microorganisms enter the body of the fetus in utero, then the newborn child receives the microflora from the mother during childbirth. The results of molecular genetic studies indicate that the process of microbial colonization of a child is determined by the characteristics of nutrition. Of great importance in the formation of normal microflora belongs to breastfeeding. The gut microbiota interacts with various parts of the body, influencing the pathogenesis of many local and systemic diseases. The most important mechanisms for the formation of diseases in children depending on anomalies in the structure of the microbiome are considered. Understanding the processes of formation of intestinal microflora allows us to develop effective methods for the prevention and correction of microecological and motor disorders in the age aspect.
About the Authors
L. A. Kharitonova
N. I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
K. I. Grigoryev
N. I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
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For citations:
Kharitonova L.A., Grigoryev K.I. The current state of the problem of intestinal microbiota according to pediatricians. Experimental and Clinical Gastroenterology. 2024;(6):176-187. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-226-6-176-187
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