Frequency of comorbid diseases in children with cholelithiasis

Abstract

Introduction. In recent years, there has been not only an increase in the incidence of cholelithiasis, but also the problem of comorbid conditions for this pathology in practical healthcare. Determining the main groups of chronic somatic diseases can identify a contingent of children where the development of cholelithiasis can be expected with a high degree of probability. Purpose of the study. To study the frequency of comorbid diseases in children with cholelithiasis. Materials and methods. The study included 146 children with cholelithiasis; according to the comorbidity index, all children were divided into three groups. The average age of the observed patients was 9.05±4.7 years, of which 61 were boys (41.8%) and 85 girls (58.2%). The obtained data were processed by MS Exel, IBM SPSS Statistics 19.0, the significance level for accepting significant differences was accepted at p ≤ 0.05. Results and discussion. The children we observed with cholelithiasis were hospitalized in a specialized gastroenterology department in 58% of cases; in 42% of cases, the detection of a stone in the gall bladder was the result of a diagnostic finding. In the group of children with cholelithiasis who have 4 or more concomitant diseases, diseases of the liver and biliary tract (X² = 12.86, p ≤ 0.02), blood diseases (X² = 8.83, p ≤ 0.012) and endocrine diseases are significantly more common. violations (X² = 8.35, p ≤ 0.05). Conclusion. According to the results of our observations, gastroenterological manifestations are leading in children with cholelithiasis. Metabolic disorders place endocrinological diseases in second place in terms of the frequency of comorbidity. The proposed laboratory and instrumental diagnostic algorithm will ensure early detection of cholelithiasis in children.