Assessment of the clinical effectiveness of use of hymecromone in combination with ursodeoxycholic acid in biliary pathology
https://doi.org/10.31146/1682-8658-ecg-223-3-65-70
Abstract
The article presents the results of a clinical evaluation of the comparative effectiveness of monotherapy with urosodeoxycholic acid and its combination with himecromone at dosages of 600 mg and 1200 mg in 368 patients with biliary pathology. The study revealed a significant improvement in the indicators of the majority of patients in the observed groups (84.7% in the UDCA group, 85.9% in the UDCA + Gimecromone 600 mg group, 87.9% in the UDCA + Gimecromone 1200 mg group). Evaluation of the effectiveness of gimecromone at a dosage of 600 mg/day and 1200 mg/day in combination with UDCA showed that the relief of symptoms of biliary dysfunction had a dose-dependent effect and the use of gimecromone at a dose of 1200 mg /day had a more pronounced clinical effect.
About the Authors
M. M. Karimov
State Institution “Republican Specialized Scientific and Practical Medical Center for Therapy and Medical Rehabilitation”
Russian Federation
Russian Federation
M. T. Rustamova
Tashkent Medical Academy
Russian Federation
Russian Federation
G. N. Sobirova
Tashkent Medical Academy
Russian Federation
Russian Federation
S. S. Khairullaeva
Tashkent Medical Academy
Russian Federation
Russian Federation
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Review
For citations:
Karimov M.M., Rustamova M.T., Sobirova G.N., Khairullaeva S.S. Assessment of the clinical effectiveness of use of hymecromone in combination with ursodeoxycholic acid in biliary pathology. Experimental and Clinical Gastroenterology. 2024;(3):65-70. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-223-3-65-70
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