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Experimental and Clinical Gastroenterology

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The development of liver cirrhosis in a patient taking long-term weight loss supplements

https://doi.org/10.31146/1682-8658-ecg-216-8-176-183

Abstract

Dietary supplements are often self-administered by patients for weight loss. However, the hepatotoxicity of such supplements remains underestimated. Liver damage is diverse: from asymptomatic reversible course to lethal fulminant hepatitis. In the case of a long unrecognized course and prolonged use of dietary supplements, irreversible structural and functional damage to the organ occurs. We present a retrospective analysis of the case histories of a patient with liver cirrhosis, who has a long history of using dietary supplements of Thai and Chinese origin, hellebore extract, during 5 years of follow-up. Despite the discontinuation of weight loss drugs, regular complex therapy, the patient has a steady progressive course of the disease. Obese patients with an increased risk of liver damage require a dynamic assessment of liver function, not only when prescribing drugs, but also when using various dietary supplements.

About the Authors

T. V. Goma
Irkutsk State Medical University Health Ministry of Russian Federation
Russian Federation


N. M. Kozlova
Irkutsk State Medical University Health Ministry of Russian Federation
Russian Federation


K. S. Boldyreva
Irkutsk State Medical University Health Ministry of Russian Federation
Russian Federation


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Review

For citations:


Goma T.V., Kozlova N.M., Boldyreva K.S. The development of liver cirrhosis in a patient taking long-term weight loss supplements. Experimental and Clinical Gastroenterology. 2023;(8):176-183. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-216-8-176-183

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