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Biliary gastritis. Pathomorphological features and differential diagnosis

https://doi.org/10.31146/1682-8658-ecg-216-8-134-140

Abstract

The review article discusses the modern pathogenetic links of biliary gastritis, namely the role of endothelial dysfunction, intestinal metaplasia in inflammation and the influence of Helicobacter pylori infection. The problem of combined damage to the mucous membrane of HP-associated and biliary gastritis remains relevant, since modern foreign studies have not come to a consensus, but most authors state increased carcinogenesis of the stomach with a positive HP status against the background of the course of pathological duodenogastric reflux. The article also presents original materials of histological examination of biliary, HP-associated, autoimmune and hyperplastic gastritis with similar morphological features, thereby demonstrating the difficulties of differential diagnosis.

About the Authors

R. A. Nasyrov
Saint- Petersburg State Pediatric Medical University
Russian Federation


Yu. A. Fominykh
Pavlov First Saint Petersburg State Medical University; Saint- Petersburg State Pediatric Medical University
Russian Federation


E. Yu. Kalinina
Saint- Petersburg State Pediatric Medical University
Russian Federation


O. A. Kizimova
Saint- Petersburg State Pediatric Medical University
Russian Federation


D. P. Kovtun
Saint- Petersburg State Budgetary Health Institution “City Clinical Oncology Center”
Russian Federation


E. V. Shcherbakova
Bureau of Forensic Medical Examination of the Leningrad Region
Russian Federation


O. S. Minina
Saint- Petersburg State Pediatric Medical University
Russian Federation


A. P. Zavitaeva
Saint- Petersburg State Pediatric Medical University
Russian Federation


References

1. Aprea G., Canfora A., Ferronetti A., Giugliano A., et аl. Morpho-functional gastric pre-and post-operative changes in elderly patients undergoing laparoscopic cholecystectomy for gallstone related disease. BMC Surg. 2012;12 (1):5. doi: 10.1186/1471-2482-12-S1-S5.

2. Othman A.A.A., Dwedar A. A.Z., ElSadek H.M., AbdElAziz H.R., et аl. Bile reflux gastropathy: Prevalence and risk factors after therapeutic biliary interventions: A retrospective cohort study. Ann Med Surg (Lond). 2021;72:103168. doi: 10.1016/j.amsu.2021.103168.

3. Nasyrov R.A., Fominykh Yu.A., Kizimova O. A., Beleventin A. B. Duodenogastric reflux and cholelithiasis: pathogenetic and clinical-morphological relationships. University therapeutic journal volume. 2023;5(1):36-52. doi: 10.56871/UTJ.2023.51.60.002. (In Russ.)@@ Насыров Р. А., Фоминых Ю. А., Кизимова О. А., Белевентин А. Б. Дуоденогастральный рефлюкс и желчнокаменная болезнь: патогенетические и клинико-морфологические взаимосвязи. University therapeutic journal volume. 2023;5(1):36-52. doi: 10.56871/UTJ.2023.51.60.002

4. Sakaguchi T., Sugihara T., Ohnita K., Fukuda D., et аl. Pyloric Incompetence Associated with Helicobactor pylori Infection and Correlated to the Severity of Atrophic Gastritis. Diagnostics (Basel). 2022;12(3):572. doi: 10.3390/diagnostics12030572.

5. Shi X., Chen Z., Yang Y., Yan S. Bile Reflux Gastritis: Insights into Pathogenesis, Relevant Factors, Carcinomatous Risk, Diagnosis, and Management. Gastroenterol Res Pract. 2022:2642551. doi: 10.1155/2022/ 2642551.

6. Kayaçetin S., Güreşçi S. What is gastritis? What is gastropathy? How is it classified? Turk J Gastroenterol. 2014;25(3):233-47. doi: 10.5152/tjg.2014.7906.

7. Maguilnik I., Neumann W. L., Sonnenberg A., Genta R. M. Reactive gastropathy is associated with inflammatory conditions throughout the gastrointestinal tract. Aliment PharmacolTher. 2012;36(8):736-43. doi: 10.1111/apt.12031.

8. Nel W., ChB M.B., Med M. (Anat Path).CME. Gastritis and gastropathy: More than meets the eye. 2013; 31(2): 37-40.

9. ICD-11 for Mortality and Morbidity Statistics (Version: 02/2022). Available at: https://icd.who.int/browse11/l-m/en#/http%3a%2f%2fid.who.int%2ficd%2fentity%2f356971565 (accessed 21.10.2022).

10. Qu X., Shi Y. Bile reflux and bile acids in the progression of gastric intestinal metaplasia. Chin Med J (Engl). 2022;135(14):1664-1672. doi: 10.1097/CM9.0000000000002290.

11. Martamala R., Djojoningrat D., Manan C., Rani A. A. The Patogenesis and Diagnosis of Bile Reflux Gastropathy.The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscop; 2001;2(1):14-20. Available at: https://pro.uptodatefree.ir/show/16636. (accessed 15.06.2022).

12. Mearin F., De Ribot X., Balboa A., Antolín M., et аl. Duodenogastric bile reflux and gastrointestinal motility in pathogenesis of functional dyspepsia. Role of cholecystectomy. Dig Dis Sci. 1995;40(8):1703-9. doi: 10.1007/BF02212691. PMID: 7648969.

13. He Q., Liu L., Wei J., Jiang J., et аl. Roles and action mechanisms of bile acid-induced gastric intestinal metaplasia: a review. Cell Death Discov. 2022;8(1):158. doi: 10.1038/s41420-022-00962-1.

14. Tatsugami M., Ito M., Tanaka S., Yoshihara M., et аl. Bile acid promotes intestinal metaplasia and gastric carcinogenesis. Cancer Epidemiol Biomarkers Prev. 2012;21(11):2101-7. doi: 10.1158/1055-9965.EPI-12-0730.

15. Dixon M.F., Mapstone N. P., Neville P. M., Moayyedi P., et аl. Bile reflux gastritis and intestinal metaplasia at the cardia. Gut. 2002;51(3):351-5. doi: 10.1136/gut.51.3.351.

16. Yu J.H., Zheng J. B., Qi J., Yang K., et аl. Bile acids promote gastric intestinal metaplasia by upregulating CDX2 and MUC2 expression via the FXR/NF-κB signalling pathway.Int J Oncol. 2019;54(3):879-892. doi: 10.3892/ijo.2019.4692.

17. Szőke A., Mocan S., Negovan A. Helicobacter pylori infection over bile reflux: No influence on the severity of endoscopic or premalignant gastric lesion development. Exp Ther Med. 2021;22(1):766. doi: 10.3892/etm.2021.10198.

18. Huang G., Wang S., Wang J., Tian L., et аl. Bile reflux alters the profile of the gastric mucosa microbiota. Front Cell Infect Microbiol. 2022;12:940687. doi: 10.3389/fcimb.2022.940687.

19. Zhang R., Ma W. Q., Fu M. J., Li J., et аl. Overview of bile acid signaling in the cardiovascular system. World J Clin Cases. 2021;9(2):308-320. doi: 10.12998/wjcc.v9.i2.308.

20. Judaki A., Norozi S., Ahmadi MRH, Ghavam S. M., et аl. Flow mediated dilation and carotid intima media thickness in patients with chronic gastritis associated with helicobacter pylori infection. Arq Gastroenterol. 2017;54(4):300-304. doi: 10.1590/S0004-2803.201700000-39.

21. Rasmi Y., Rouhrazi H., Khayati-Shal E., Shirpoor A., et аl. Association of endothelial dysfunction and cytotoxin-associated gene A-positive Helicobacter pylori in patients with cardiac syndrome X. Biomed J. 2016;39(5):339-345. doi: 10.1016/j.bj.2016.01.010.

22. Xia X., Zhang L., Wu H., Chen.F, et аl. CagA+Helicobacter pylori, Not CagA-Helicobacter pylori, Infection Impairs Endothelial Function Through Exosomes-Mediated ROS Formation. Front Cardiovasc Med. 2022;9:881372. doi: 10.3389/fcvm.2022.881372.

23. Morgan D., MD, MPH. Gastric intestinal metaplasia. Available at: https://pro.uptodatefree.ir/show/16636. (accessed 15.06.2022).

24. Azer S.A., Akhondi H. Gastritis. 2022. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. PMID: 31334970.

25. Owen D. A. The morphology of gastritis. YaleJBiolMed. 1996;69(1):51-60. PMID: 9041689; PMCID: PMC2588968.

26. Voutilainen M., Juhola M., Färkkilä M., Sipponen P. Foveolar hyperplasia at the gastric cardia: prevalence and associations. J ClinPathol. 2002;55(5):352-4. doi: 10.1136/jcp.55.5.352.

27. Kumar V. Abbas A. Fausto N. Aster D. The basis of pathological diseases according to Robbins and Kotranu. Translate. edd. Kogan EA, Serova RA, Dubovoy EA, Pavlova KA. Moscow. Logosphere Publ. 2016;(2): 882. (in Russ.)@@ Кумар В., Аббас А., Фаусто Н., Астер Д. Основы патологии заболеваний по Роббинсу и Котрану //Пер. с англ./Под ред. Коган ЕА, Серова РА, Дубовой ЕА, Павлова КА - М.: Логосфера. - 2016. - Т. 2. - С. 882.

28. Geetika K.C., Shiva Raj K. C. Mast cells in relation to Helicobacter pylori and chronic active gastritis. Journal of Pathology of Nepal;2015; 5: 806-809.

29. Lv Y.P., Teng Y. S., Mao F. Y., Peng L. S., et аl. Helicobacter pylori-induced IL-33 modulates mast cell responses, benefits bacterial growth, and contributes to gastritis. Cell Death Dis. 2018;9(5):457. doi: 10.1038/s41419-018-0493-1.

30. Kato M., Uedo N., Toth E., Shichijo S., et аl. Wurm Johansson G. Differences in image-enhanced endoscopic findings between Helicobacter pylori -associated and autoimmune gastritis. Endosc Int Open. 2021;9(1): E22-E30. doi: 10.1055/a-1287-9767.

31. Coati I., Fassan M., Farinati F., Graham D. Y., et аl. Autoimmune gastritis: Pathologist’s viewpoint. World J Gastroenterol. 2015;21(42):12179-89. doi: 10.3748/wjg.v21.i42.12179.

32. Neumann W.L., Coss E., Rugge M., Genta R. M. Autoimmune atrophic gastritis - pathogenesis, pathology and management. Nat Rev Gastroenterol Hepatol. 2013;10(9): 529-41. doi: 10.1038/nrgastro.

33. Gómez Zuleta M. A., Ruíz Morales O. F., Riveros J. Menetrier disease: Case report with video.Asociaciones Colombianas de Gastroenterología, Endoscopia digestiva, Coloproctología y Hepatología.2019; 34:2. doi: 10.22516/25007440.396.

34. Rubio C.A., Ost A., Kato Y., Yanagisawa A., et аl. Hyperplastic foveolar gastropathies and hyperplastic foveolar gastritis. APMIS. 1997;105(10):784-92. doi: 10.1111/j.1699-0463.1997.tb05084.x.

35. Gore M., Bansal K., Jadhav N. Menetrier Disease. 2022. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022. PMID: 33085301.

36. Huh W.J., Coffey R. J., Washington M. K. Ménétrier’s Disease: Its Mimickers and Pathogenesis. J Pathol Transl Med. 2016;50(1):10-6. doi: 10.4132/jptm.2015.09.15.

37. Byun J, Kwon S, Oh SY, Lee KG, et аl. Laparoscopic management of hypertrophic hypersecretory gastropathy with protein loss: a case report. Asian J Endosc Surg. 2014 Jan;7(1):48-51. doi: 10.1111/ases.12062. PMID: 24450343.


Review

For citations:


Nasyrov R.A., Fominykh Yu.A., Kalinina E.Yu., Kizimova O.A., Kovtun D.P., Shcherbakova E.V., Minina O.S., Zavitaeva A.P. Biliary gastritis. Pathomorphological features and differential diagnosis. Experimental and Clinical Gastroenterology. 2023;(8):134-140. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-216-8-134-140

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