Preview

Experimental and Clinical Gastroenterology

Advanced search

GUT AND VAGINAL MICROBIOTA IN FEMALE WITH REPRODUCTIVE DISORDERS ASSOCIATED WITH GASTROINTESTINAL DISTURBANCE

Abstract

The aim of research - a comparative study of the microflora of the vagina and bowel in women with secondary infertility and gastrointestinal distress. Materials and methods. We examined gut and vaginal microbiota in 17 infertile women according to the presence or absence of gastrointestinal diseases. We used a standard procedure for microbiological examination. Results. Certain changes of bacterial load and composition in both reservoirs were established. They allowed us to conclude the same trends in characterizing of the developing dysbiosis. Conclusion. Thus, the simultaneous studying of vaginal and gut microflora seems to be rational during the examination of women with childbearing disorders. It could possibly increase the treatment efficacy and/or prevent the development of some pathology.

About the Authors

A. P. Godovalov
Public budgetary educational institution of higher education «Acad. E. A. Wagner Perm State Medical University» of the Ministry of Healthcare of the Russia
Russian Federation


N. S. Karpunina
Public budgetary educational institution of higher education «Acad. E. A. Wagner Perm State Medical University» of the Ministry of Healthcare of the Russia
Russian Federation


T. I. Karpunina
Public budgetary educational institution of higher education «Acad. E. A. Wagner Perm State Medical University» of the Ministry of Healthcare of the Russia
Russian Federation


References

1. Palomba S., Sereni G., Falbo A. et al. Inflammatory bowel diseases and human reproduction: A comprehensive evidencebased review. World J. Gastroenterol., 2014, vol. 20, no. 23, pp. 7123-7136.

2. Анкирская А. С., Муравьева В. В. Интегральная оценка состояния микробиоты влагалища, диагностика оппортунистических вагинитов. Медицинская технология. М.: ФГБУ «НЦ АГиП им. В. И. Кулакова» Минздравсоцразвития России, 2011, 20 c.

3. Липова Е. В., Болдырева М. Н., Трофимов Д. Ю., Витвицкая Ю. Г. Урогенитальные инфекции, обусловленные условно-патогенной биотой у женщин репродуктивного возраста (Клинико-лабораторная диагностика), Пособие для врачей, М.; 2009, 30 с.

4. Sherrard J., Donders G., White D., Jensen J. S. European (IUSTI/WHO) guideline on the management of vaginal discharge. International journal of STD & AIDS, 2011, vol. 22, no. 8, pp. 421-429.

5. Рищук С. В., Понченко О. Е., Малышева А. А. Эндогенная микробиота влагалища и ее регуляция. Бюллетень Оренбургского научного центра УрО РАН (электронный журнал), 2013, № 4, c. 1-30.

6. Гасанова Т. А. Микробиоценозы при воспалительных заболеваниях репродуктивных органов женщин и перинатальной патологии: Автореф. дис. … докт. мед. наук. Саратов, 2006, 48 c.

7. Плотко Е. Э., Донников А. Е., Ворошилина Е. С. и соавт. Биоценоз влагалища с точки зрения количественной ПЦР: что есть норма? Акушерство и гинекология, 2011, № 1, c. 66-70.

8. Меджидова М. К., Зайдиева З. С., Вересова А. А. Микробиоценоз влагалища и факторы, влияющие на его состояние. http://www.remedium.ru/drugs/detail.php? ID=60978

9. Reilly N. R., Fasano A., Green P. H. Presentation of celiac disease. Gastrointest Endosc Clin N Am, 2012, vol. 22, pp. 613-21.

10. Choi J. M., Lebwohl B., Wang J. et al. Increased prevalence of celiac disease in patients with unexplained infertility in the United States. J. Reprod. Med, 2011, vol. 56, no. 5-6, pp. 199-203.

11. Khosla R., Willoughby C. P., Jewell D. P. Crohn’s disease and pregnancy. Gut, 1984, vol. 25, pp. 52-56.

12. Olsen K. O., Joelsson M., Laurberg S., Oresland T. Fertility after ileal pouch-anal anastomosis in women with ulcerative colitis. Br. J. Surg, 1999, vol. 86, pp. 493-495.

13. Cornish J. A., Tan E., Teare J. et al. The effect of restorative proctocolectomy on sexual function, urinary function, fertility, pregnancy and delivery: a systematic review. Dis. Colon. Rectum, 2007, vol. 50, pp. 1128-1138.

14. Antonio M. A., Rabe L. K., Hillier S. L. Colonization of the rectum by Lactobacillus species and decreased risk of bacterial vaginosis. J. Infect. Dis, 2005, vol. 192, pp. 394-8.

15. Reid G., Bruce A. W., Fraser N. et al. Oral probiotics can resolve urogenital infections. FEMS Immunol. Med. Microbiol, 2001, vol. 30, pp. 49-52.

16. El Aila N. A., Tency I., Saerens B. et al. Strong correspondence in bacterial loads between the vagina and rectum of pregnant women. Res. Microbiol, 2011, vol. 162, pp. 506-13.

17. Жук С. И., Ночвина Е. А. Современный подход к коррекции нарушений овариально-менструального цикла. Здоровье женщины, 2006, Т. 1, № 25, c. 92-95.


Review

For citations:


Godovalov A.P., Karpunina N.S., Karpunina T.I. GUT AND VAGINAL MICROBIOTA IN FEMALE WITH REPRODUCTIVE DISORDERS ASSOCIATED WITH GASTROINTESTINAL DISTURBANCE. Experimental and Clinical Gastroenterology. 2016;(6):109-113. (In Russ.)

Views: 6440


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1682-8658 (Print)