Recurrent candidiasis of the oropharynx and esophagus in a patient with immune dysfunction after thymusectomy
https://doi.org/10.31146/1682-8658-ecg-204-8-190-194
Abstract
A clinical case of a patient who underwent a thymusectomy for thymoma at the age of 50 is presented. Subsequently, the patient developed immune dysfunction with recurrent esophageal candidiasis and oropharyngeal candidiasis caused by Candida albicans. The patient also suffers from persistent widespread mycosis of the skin and nail plates caused by Trichophyton rubrum, autoimmune gastritis and benign neoplasms of the oral cavity and intestines. Repeated courses of treatment with fluconazole led to the emergence of Candida albicans resistance to azole antimycotics. Treatment with irrigation of Amphotericin solution B in the oropharynx and in the esophagus was effective.
About the Authors
M. A. Shevyakov
North-Western State Medical University named after I. I. Mechnikov
Russian Federation
O. V. Paramonova
North-Western State Medical University named after I. I. Mechnikov
Russian Federation
L. P. Kotrekhova
North-Western State Medical University named after I. I. Mechnikov
Russian Federation
V. L. Mirzoyan
North-Western State Medical University named after I. I. Mechnikov
Russian Federation
O. A. Shurpitskaya
North-Western State Medical University named after I. I. Mechnikov
Russian Federation
E. V. Frolova
North-Western State Medical University named after I. I. Mechnikov
Russian Federation
V. S. Mitrofanov
North-Western State Medical University named after I. I. Mechnikov
Russian Federation
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For citations:
Shevyakov M.A.,
Paramonova O.V.,
Kotrekhova L.P.,
Mirzoyan V.L.,
Shurpitskaya O.A.,
Frolova E.V.,
Mitrofanov V.S.
Recurrent candidiasis of the oropharynx and esophagus in a patient with immune dysfunction after thymusectomy. Experimental and Clinical Gastroenterology. 2022;(8):190-194.
(In Russ.)
https://doi.org/10.31146/1682-8658-ecg-204-8-190-194
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