EPIDEMIOLOGICAL, CLINICAL AND GENETIC CHARACTERISTICS OF ANORECTAL MALFORMATIONS (REVIEW)
Abstract
The review presents an analysis of current data on the epidemiology, etiology, clinical and genetic characteristics of congenital anorectal malformations (AM). According to international registers of congenital malformations prevalence of the AM varies from 2 to 5 per 10,000 births. There was no change in the prevalence over time of AM (absence of temporal trends). Most studies have indicated the predominance of males among patients with AM. Approximately 40 - 70% of patients with AM have congenital malformations of other organs and systems. The data on the participation of genetic and environmental factors in the origin of the AM. A brief clinical and genetic characteristics of the most common syndromes (association) with the AM.
About the Authors
Yu. V. Vydrych
I. M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
N. S. Demikova
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Yu. N. Filyushkin
Moscow Regional Research Clinical Institute named after M. F. Vladimirsky
Russian Federation
Russian Federation
S. G. Kalinenkova
Moscow Regional Research Clinical Institute named after M. F. Vladimirsky
Russian Federation
Russian Federation
M. A. Podolnaya
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
A. S. Lapina
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
A. E. Mashkov
Moscow Regional Research Clinical Institute named after M. F. Vladimirsky
Russian Federation
Russian Federation
A. Yu. Asanov
I. M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Vydrych Yu.V., Demikova N.S., Filyushkin Yu.N., Kalinenkova S.G., Podolnaya M.A., Lapina A.S., Mashkov A.E., Asanov A.Yu. EPIDEMIOLOGICAL, CLINICAL AND GENETIC CHARACTERISTICS OF ANORECTAL MALFORMATIONS (REVIEW). Experimental and Clinical Gastroenterology. 2016;(5):58-64. (In Russ.)
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