Mikrobiota esophagus, stomach and duodenal estate in normal and pathology
https://doi.org/10.31146/1682-8658-ecg-200-4-169-178
Abstract
Aim. Revealing the level and signifi cance of Helicobacter pylori (H. pylori) in the normobiocenosis and disbacteriosis of mucosal microbiota in the esophagus, stomach and duodenum.
Material and methods. Qualitative and quantitative composition of the mucosal microbiota was defi ned in biopsy specimens from diff erent parts of esophagus, stomach and duodenum in addition to clinical and histological examination in 50 healthy volunteers, 106 ulcer duodenum patients, 24 patients with gastric ulcer, 36 with chronic gastritis and 24 with chronic esophagitis.
Results. H. pylori is involved into normomicrobiocenosis of the mocosal microbiota and take part of main defensive function of gastroduodenal tract. Excerbation of peptic ulcer, chronic gastritis and esophagitis is accompanied with the reduction H. pylori in most cases, though the scar formation occurs both with and without presence of H. pylori.
Conclusion. The colonization of the esophagus, stomach and duodenum by H. pylori has no infection process and play the independent role in the development of the ulcer disease, gastritis and esophagitis and does not require the eradication.
About the Authors
V. M. Chervinets
Tver State Medical University
Russian Federation
Russian Federation
Vyacheslav M. Chervinets, MD, PhD, Head of Department of Microbiology and Virology with the Cypse of Immunology
4, Sovetskaya St., Tver, 170100
Yu. V. Chervinets
Tver State Medical University
Russian Federation
Russian Federation
Yuliya V. Chervinets, MD, PhD of Department of Microbiology and Virology with the Cypse of Immunology
4, Sovetskaya St., Tver, 170100
D. V. Ganzya
Tver State Medical University
Russian Federation
Russian Federation
Ganzya Denis Viktorovich, Assistant Department of Neurology, Rehabilitation and Neurosurgery
4, Sovetskaya St., Tver, 170100
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Review
For citations:
Chervinets V.M., Chervinets Yu.V., Ganzya D.V. Mikrobiota esophagus, stomach and duodenal estate in normal and pathology. Experimental and Clinical Gastroenterology. 2022;(4):169-178. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-200-4-169-178
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