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Narrow-band imaging Dual focus endoscopy capabilities in diff erential diagnosis of intestinal metaplasia types

https://doi.org/10.31146/1682-8658-ecg-201-5-12-16

Abstract

Stomach cancer has an important place in medicine. Unfortunately, diagnosis of gastric cancer is being established in majority of cases at the IV stage. So, yt is necessary to detect tumors at the earliest stages of carcinogenesis and to evaluate and treat precancerous diseases, such as gastric atrophy and intestinal metaplasia.
Aims: To estimate the value of Narrow-band imaging Dual focus (NBI Dual Focus) endoscopy capabilities in differential diagnosis of intestinal metaplasia types. We evaluated the data of Russian and foreign articles on this topic from 2011 to 2021. In our study 46 patients with suspected intestinal metaplasia admitted to Nizhny Novgorod Oncology Dispensary. We have performed multimodal endoscopy, including White light endoscopy (WLI), narrow-band imaging (NBI, WLI, BLI — 28) and Dual focus endoscopy (18). Sydney system based multifocal biopsy and targeted biopsy of IM foci were performed in all cases.
Results: Verification of intestinal metaplasia, visualized with WLI, was confirmed in only 59% cases. However, intestinal metaplasia, observed with NBI, was confirmed by pathology in 100% cases. NBI Dual Focus endoscopy made possible to differentiate complete and incomplete intestinal metaplasia also in all patients.
Conclusions: Intestinal metaplasia can be successfully diagnosed with NBI endoscopy. Differential diagnosis of types of intestinal metaplasia and other variants of gastric mucosa metaplasia is possible using narrow-spectrum endoscopy with dual focus (NBI Dual Focus).

About the Authors

R. A. Gagaev
Regional Nizhniy Novgorod State Oncological Hospital
Russian Federation

Roman A. Gagaev, endoscopist

603093, Nizhny Novgorod, st. Delovaya, build.11/1



S. S. Pirogov
P. A. Herzen Moscow Cancer Research Institute, branch of National Medical Research Radiology Center
Russian Federation

Sergey S. Pirogov, M.D., Ph.D., Head of endoscopy division

125284, Moscow, 2nd Botkinskiy proezd, build. 3



A. A. Mitrakov
Regional Nizhniy Novgorod State Oncological Hospital
Russian Federation

Alexandr A. Mitrakov, Head of endoscopy division

603093, Nizhny Novgorod, st. Delovaya, build.11/1



R. S. Smirnova
Regional Nizhniy Novgorod State Oncological Hospital
Russian Federation

Raisat S. Smirnova, Chief of Endoscopy Unit

603093, Nizhny Novgorod, st. Delovaya, build.11/1



D. A. Davydova
Regional Nizhniy Novgorod State Oncological Hospital
Russian Federation

Diana A. Davydova, Ph.D., Chief of Pathology Department

603093, Nizhny Novgorod, st. Delovaya, build.11/1



S. V. Gamayunov
Regional Nizhniy Novgorod State Oncological Hospital; A. Tsyb Medical Radiological Research Center —branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation (A. Tsyb MRRC)
Russian Federation

Sergey V. Gamayunov, Ph.D., Head; Visiting Fellow Unit

603093, Nizhny Novgorod, st. Delovaya, build.11/1
249036, Kaluga region, Obninsk, Korolev str., build. 4



A. D. Kaprin
P. A. Herzen Moscow Cancer Research Institute, branch of National Medical Research Radiology Center
Russian Federation

Andrey D. Kaprin, M.D., Ph.D., Academician of RAS, Head Medical Center

125284, Moscow, 2nd Botkinskiy proezd, build. 3



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For citations:


Gagaev R.A., Pirogov S.S., Mitrakov A.A., Smirnova R.S., Davydova D.A., Gamayunov S.V., Kaprin A.D. Narrow-band imaging Dual focus endoscopy capabilities in diff erential diagnosis of intestinal metaplasia types. Experimental and Clinical Gastroenterology. 2022;(5):12-16. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-201-5-12-16

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