Clinical-endoscopic and morphological aspects of autoimmune gastritis
https://doi.org/10.31146/1682-8658-ecg-200-4-14-19
Abstract
Purpose of the study. to analyze cases of autoimmune gastritis, features of its clinical course, methods of laboratory diagnostics, typical endoscopic and morphological signs.
Materials and methods. 32 patients (25 women, 7 men) with confi rmed autoimmune gastritis, performed clinical and laboratory examination, esophagogastroduodenoscopy, morphological assessment according to OLGA.
Results. Autoimmune gastritis is characterized by a low-symptom course, the development of iron and B12-defi ciency states, low values of serum pepsinogens, hypergastrinemia, in 25% of cases it is combined with H. pylori- associated gastritis. In 59.38% of the examined, autoimmune gastritis proceeds with endoscopic signs of total atrophy of the gastric mucosa, according to OLGA stage II prevails — 55% and II degree — 75% of the examined. The development of gastric neuroendocrine tumors were recorded in 2 patients.
About the Authors
S. V. Shchelochenkov
The Immanuel Kant Baltic Federal University
Russian Federation
Russian Federation
Sergey V. Shchelochenkov, PhD, Associate professor department of therapy medical institute
14 A. Nevskogo str., Kaliningrad, 236016
O. N. Guskova
Tver State Medical University
Russian Federation
Russian Federation
Oksana N. Guskova, PhD, Head of the Department of Pathological Anatomy
4 Sovietskaya str., Tver, 170100
D. S. Bordin
Tver State Medical University; A. S. Loginov Moscow Clinical Scientific and Practical Center; A. I. Yevdokimov Moscow State University of Medicine and Dentistry
Russian Federation
Russian Federation
Dmitry S. Bordin, MD, PhD, Head of the Department of Pancreatic, Biliary and upper digestive tract disorders; professor of the department of outpatient therapy and family medicine; professor of the department of propaedeutic of internal diseases and gastroenterology
Scopus Author ID: 6602087114, Researcher ID: M-4708–2017
4 Sovietskaya str., Tver, 170100
86, sh. Entuziastov, Moscow, 111123
20 / 1, Delegatskay str., Moscow, 127473
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Review
For citations:
Shchelochenkov S.V., Guskova O.N., Bordin D.S. Clinical-endoscopic and morphological aspects of autoimmune gastritis. Experimental and Clinical Gastroenterology. 2022;(4):14-19. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-200-4-14-19
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