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Экспериментальная и клиническая гастроэнтерология

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Зонулин-регулируемая барьерная функция кишечника и полиморбидность

https://doi.org/10.31146/1682-8658-ecg-198-2-111-120

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Аннотация

Одним из главных достижений в понимании роли проницаемости кишечника является открытие человеческого аналога токсина zonulaoccludens, названного зонулином. В данном обзоре литературы описаны различные заболевания, в том числе и инфекция COVID-19, в патогенезе которых участвует физиологический модулятор межклеточных плотных контактов - зонулин. Обсуждается возможная роль зонулина в развитии полиморбидности.

Об авторах

К. Н. Халаиджева
ФГАОУ ВО Первый Московский государственный медицинский университет им. И. М. Сеченова Минздрава России (Сеченовский Университет)
Россия


В. Н. Дроздов
ФГАОУ ВО Первый Московский государственный медицинский университет им. И. М. Сеченова Минздрава России (Сеченовский Университет)
Россия


Е. В. Ших
ФГАОУ ВО Первый Московский государственный медицинский университет им. И. М. Сеченова Минздрава России (Сеченовский Университет)
Россия


Л. Б. Лазебник
ФГБОУ ВО «Московский государственный медико- стоматологический университет им. А. И. Евдокимова» Минздрава России
Россия


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Рецензия

Для цитирования:


Халаиджева К.Н., Дроздов В.Н., Ших Е.В., Лазебник Л.Б. Зонулин-регулируемая барьерная функция кишечника и полиморбидность. Экспериментальная и клиническая гастроэнтерология. 2022;(2):111-120. https://doi.org/10.31146/1682-8658-ecg-198-2-111-120

For citation:


Khalaidzheva K.N., Drozdov V.N., Shikh E.V., Lazebnik L.B. Zonulin-regulated intestinal barrier function and multymorbidity. Experimental and Clinical Gastroenterology. 2022;(2):111-120. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-198-2-111-120

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