A practical case: features of the autoimmune insulin syndrome diagnosis
https://doi.org/10.31146/1682-8658-ecg-195-11-100-103
Abstract
Autoimmune Insulin syndrome (AIS), also named Hirata disease, is a rare condition characterized by hypoglycemic episodes due to the presence of high titers of insulin autoantibodies (IAA). AIS is a form of immune-mediated hypoglycemia, which develops when a triggering factor (medication or a viral infection) acts on an underlying predisposing genetic background. The diagnosis of IAS is challenging, requiring a careful workup aimed at excluding other causes of hyperinsulinemic hypoglucemia. The article presents a case of Hirata disease diagnosing of a patient of the therapy department of the Multidisciplinary Medical Center of the Bank of Russia.
Purpose: Determining of the features of the diagnosis of Autoimmune Insulin syndrome (Hirata disease)
Materials and methods: the article presents a clinical case of the diagnosis of Autoimmune insulin syndrome (Hirata disease), focuses on the diagnostic significance of laboratory tests. The article is intended for general practitioners, endocrinologists, gastroenterologists.
About the Authors
N. A. Zykova
Multidisciplinary Medical Center of the Bank of Russia
Russian Federation
Russian Federation
Nataliya A. Zykova, Higher category of endocrinology
66, Sevastopolsky prospect, 117593, Moscow
E. V. Ignashina
Multidisciplinary Medical Center of the Bank of Russia
Russian Federation
Russian Federation
Elena V. Ignashina, Cand. Sc. (medicine), Higher category of endocrinology
66, Sevastopolsky prospect, 117593, Moscow
E. D. Li
Multidisciplinary Medical Center of the Bank of Russia
Russian Federation
Russian Federation
Elena D. Li, D. Sc. (medicine), Higher category of therapy
66, Sevastopolsky prospect, 117593, Moscow
V. V. Kugryshev
Multidisciplinary Medical Center of the Bank of Russia
Russian Federation
Russian Federation
endocrinologist
66, Sevastopolsky prospect, 117593, Moscow
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Review
For citations:
Zykova N.A., Ignashina E.V., Li E.D., Kugryshev V.V. A practical case: features of the autoimmune insulin syndrome diagnosis. Experimental and Clinical Gastroenterology. 2021;(11):100-103. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-195-11-100-103
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