Metachronous multiple primary cancer of the pancreatic head and liver: a case of hepatocellular carcinoma 10 years after pancreatoduodenal resection
https://doi.org/10.31146/1682-8658-ecg-195-11-79-83
Abstract
The Aim. Study of a clinical case of metachronous primary multiple cancer of the head of the pancreas and liver.
Materials and methods. The work was carried out with modern domestic and foreign literature sources devoted to the problem of primary multiple malignant neoplasms. A retrospective analysis of the patient’s clinical and anamnestic data was performed, the necessary medical documentation was studied.
Results. In 2011, a pancreatoduodenal resection was performed on a patient for ductal adenocarcinoma of the head of the pancreas. In 2021, an MRI scan revealed a formation in S5-S6 with dimensions up to 34x35x29 mm. According to the histological examination of the biopsy material, hepatocellular carcinoma was confirmed. Resection of the 5th segment of the liver was performed in the conditions of the NMIC Oncology in Rostov-on-Don.
Conclusion. The presented case of primary multiple cancer of the head of the pancreas and hepatocellular carcinoma of the liver is of direct interest both from the point of view of oncological surgery and chemotherapy.
About the Authors
O. I. KitRussian Federation
Oleg I. Kit, General Director, Ph.D. (Med.), Professor, Corresponding Member of the Russian Academy of Sciences. Scopus Author ID: 55994103100, Researcher ID: U-2241–2017
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
E. N. Kolesnikov
Russian Federation
Evgeniy N. Kolesnikov, M.D. (Med.), Head of Department of Abdominal Oncology № 1 with a Group of Roentgen Endovascular Methods of Diagnostics and Treatment, oncologist. Scopus Author ID: 57190297598
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
V. S. Trifanov
Russian Federation
Vladimir S. Trifanov, Ph.D. (Med.), Chief researcher of Department Of Abdominal Oncology № 1 with a Group of Roentgen Endovascular Methods of Diagnostics and Treatment, surgeon
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
T. O. Lapteva
Russian Federation
Tatiana O. Lapteva, Ph.D. (Med.), Head of Department of Pathological Anatomy
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
M. V. Voloshin
Russian Federation
Mark V. Voloshin, pathologist
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
M. Yu. Mesheryakova
Russian Federation
Milana Yu. Mesheryakova, fellow doctor
344037, Rostov region, Rostov-on-Don, 14 liniya str., 63
References
1. Kit O.I., Dzhenkova E. A., Mirzoyan E. A., et al. Molecular genetic classification of colorectal cancer subtypes: current state of the problem. South Russian Journal of Cancer. 2021;2(2):50–56. (In Russ.) doi: 10.37748/26869039–2021–2–2–6.
2. Gantsev Sh. Kh., Starinskiy V. V., Rakhmatulina I. R., Kudryashova L. N., Sultanov R. Z., Sakayeva D. D. Ambulatorno-poliklinicheskaya onkologiya [Outpatient oncology]. Moscow. GEOTAR-Media Publ., 2014. 448 p. (In Russ.)
3. Popova T.N., Fedorov V. E., Kharitonov B. S. Pervichnomnozhestvennyye sinkhronnyye zlokachestvennyye novoobrazovaniya pishchevaritelnoy sistemy [Primarymultiple synchronous malignant neoplasms of the digestive system]. Meditsinskiy almanakh. 2011, no. 5, pp. 76–79. (In Russ.)
4. Gorelikova O. N. Pervichno-mnozhestvennyye zlokachestvennyye opukholi [Primary-multiple malignant tumors]. Vestnik RONTs im. N. N. Blokhina RAMN. 1992, no. 4, pp. 53–61. (In Russ.)
5. Goncharenko G. V. Primary multiple malignat tumors most common localizations cancer – cancer study clinics. Research and Practical Medicine Journal. 2015;2(4):59–65. (In Russ.) doi: 10.17709/2409–2231–2015–2–4–59–65.
6. Yadav V., Panda D., Patidar Y., Bihari C. A rare case report: carcinoma pancreas with hepatocellular carcinoma. Indian J Palliat Care. 2014;20(1): 53–6. doi: 10.4103/0973–1075.125562.
7. Kitahama T., Yamane H., Mohri K., et al. A case of intraductal papillary neoplasm of the bile duct accompanied by intraductal papillary mucinous neoplasm of the pancreas and hepatocellular carcinoma. Clin J Gastroenterol. 2021 Oct;14(5):1536–1543. doi: 10.1007/s12328–021–01461-z.
8. Kaprin A.D., Starinskiy V. V., Shakhzadovoa A. O. Zlok achestvennyye novoobrazovaniya v Rossii v 2019 godu (zabolevayemost i smertnost) [Malignant neoplasms in Russia in 2019 (morbidity and mortality)]. Moscow. National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation Publ., 2020. 239 p. (In Russ.)
Review
For citations:
Kit O.I., Kolesnikov E.N., Trifanov V.S., Lapteva T.O., Voloshin M.V., Mesheryakova M.Yu. Metachronous multiple primary cancer of the pancreatic head and liver: a case of hepatocellular carcinoma 10 years after pancreatoduodenal resection. Experimental and Clinical Gastroenterology. 2021;(11):79-83. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-195-11-79-83