Thyrotoxic hepatitis during pregnancy (clinical case)
https://doi.org/10.31146/1682-8658-ecg-194-10-155-158
Abstract
A rare clinical case of thyrotoxic hepatitis detected in a pregnant woman is presented. A diagnostic search was carried out to clarify the cause of hepatitis, during which the pathology of the thyroid gland was revealed. The patient was prescribed adequate therapy with a thyrostatic drug, which in a short time allowed to achieve a significant decrease in the activity of the hepatic pathological process, which made it possible to prolong pregnancy.
About the Authors
A. V. AparkinaRussian Federation
Alena V. Aparkina - Department of Hospital Therapy of medical faculty, Assistant, PhD in Medicine.
Bolshaya Kazachya str., 112, Saratov, 410012.
E. I. Kashkina
Russian Federation
Elena I. Kashkina - Department of Hospital Therapy of medical faculty, Professor, MD.
Bolshaya Kazachya str., 112, Saratov, 410012.
A. A. Markova
Russian Federation
Anna A. Markova - Department of Hospital Therapy of medical faculty, Assistant, PhD in Medicine.
Bolshaya Kazachya str., 112, Saratov, 410012.
K. S. Azarkina
Russian Federation
Kseniya S. Azarkina – Student.
Bolshaya Kazachya str., 112, Saratov, 410012.
V. O. Darbinayn
Russian Federation
Volodiya O. Darbinayn – Student.
Bolshaya Kazachya str., 112, Saratov, 410012.
References
1. Dedov I. I., Melnichenko G. A., Fadeev V. V. Endo-krinologiya. Moscow. GEOTAR-Media Publ., 2007. (In Russ.)
2. Ross D. S., Burch H. B., Cooper D. S., et al. 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidismand Other Causes of Thyrotoxicosis. Thyroid. 2016;26(10):1343-1421. Doi: 10.1089/thy.2016.0229.
3. de Campos Mazo D. F., de Vasconcelos G. B., Pereira M. A., et al. Clinical spectrum and therapeutic approach to hepatocellular injury in patients with hyperthyroidism. Clin Exp Gastroenterol. 2013;6:9-17. Doi: 10.2147/ceg.S393585.
4. Khemichian S., Fong T. L. Hepatic dysfunction in hyperthyroidism. Gastroenterol Hepatol (N Y). 2011;7(5):337-339. PMC3127041.
5. Shetty S., Rajasekaran S., Venkatakrishnan L. Grave's disease and primary biliary cirrhosis-an unusual and challenging association. J Clin Exp Hepatol. 2014;4(1):66-67. Doi: 10.1016/j.jceh.2013.08.001
6. Pikulev D. V., Klemenov A. V. Thyrotoxic hepatitis. Problemy endokrinologii. 2017;63(1):46-0. (InRuss.) Doi: 10.14341/probl201763146-50.
7. Fadeyev V. V., Lesnikova S. V. Hypothyroidism and isolated hypothyroxinemia duri ngpregnancy. Clinical and Experimental Th yroidology. 2011;7(1):6-14 (In Russ.) Doi: 10.14341/ket2011716-14.
8. Lovkova J. S., Potin V. V., Tkachenko N. N., et al. Treatment of diffuse toxic goiter during pregnancy. Journal of obstetrics and women's diseases. 2017; 66 (3): 89-96. (In Russ.) Doi: 10.17816/JOWD66389-96.
9. Kishore K., Adhya A. K. Graves' disease with Pancytopenia and Hepatic Dysfunction: A Rare Case Presentation. Indian Journal of Nuclear Medicine. 2019;34:38-41. Doi: 10.4103/ijnm.IJNM_134_18.
10. Pavlova T. V., Malutina E. A., Petrukhin V. A. Effect of thyroid diseases in the course of pregnancy and delivery. literary review. Fundamental research. 2011; 3:15-21. (in Russ.) Doi: fundamental-research.ru/ru/article/view?id=21112.
11. Troshina E. A., Sviridenko N. Yu., Vanushko V. E., et al. The federal clinical recommendations on diagnostics and treatment of toxic goiter. Problems of Endocrinology. 2014;60(6):67-77. (In Russ.) Doi: 10.14341/probl201460667-77.
Review
For citations:
Aparkina A.V., Kashkina E.I., Markova A.A., Azarkina K.S., Darbinayn V.O. Thyrotoxic hepatitis during pregnancy (clinical case). Experimental and Clinical Gastroenterology. 2021;(10):155-158. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-194-10-155-158