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Experimental and Clinical Gastroenterology

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The premorbid background and the most significant predictors of the development chronic gastroduodenal pathology in children

https://doi.org/10.31146/1682-8658-ecg-193-9-78-85

Abstract

The study features of premorbid background and the most significant predictors of the development of chronic gastroduodenal pathology in children and adolescents of school age. Materials and methods. The results of screening questioning of schoolchildren with chronic gastroduodenal pathology (CGDP) - n=286, and practically healthy schoolchildren - n=1023, from 6 to 15 years agо. The survey conducted according to the questionnaire developed by us, which includes 24 questions. The relative risk (RR) calculated using traditional statistical formulas with a confidence interval limit 95% CI (confidence interval). Results. In this study, it was found that the main nutritional reason for the development of СGDP in schoolchildren is a malnutrition - 69.2%, RR=2.25 (CI=1.81-2.79), and food for fast food - 65.0%, RR=4.19 (CI=3.45-5.09). The least observed was the abuse of spicy food - 4.9%, RR=1.24 (CI=0.80-1.91). The 42.7% of patients were constantly in a state of heightened psychoemotional stress - RR=1.6 (CI=1.32-1.93). Helicobacter pylori (HP) - infection was diagnosed in 57.7% of patients - RR=4.84 (CI=4.04-5.79), 29.0% of patients underwent acute intestinal infections - RR=2.74 (CI=2.29-3.27), and 62.3% had a history of hereditary burden of chronic diseases of the gastrointestinal tract - RR=1.65 (CI=1.34-2.02) Conclusion. The most significant predictors and premorbid backgrounds for the development of СGDP in schoolchildren are HP-infection (RR=4.84; CI=4.04-5.79; RRR=3.84), food for fast food (RR=4.19; CI=3.45-5,09; RRR=3.20) with the development of overweight and obesity (RR=3.64; CI=2.97-4.47; RRR=2.64), the presence of chronic foci of infection (RR=2.58; CI=2.05-3.23; RRR=1.58).

About the Author

Sh. T. Turdieva
Tashkent Pediatric Medical Institute
Uzbekistan

Shokhida T. Turdieva - DSc, associate professor of the Department “Family Medicine No. 1”; SPIN: 5520–6507 ORCID: 0000-0001-7042-5387, Researcher ID: L-6078–2018, SCOPUS Author ID: 57189496193

100140, 223 Bogi- Shamol st., Tashkent



References

1. A Healthy Start in Life: Report of the Global Consultation on Child and Adolescent Health and Development, 2016. WHO/CAH/02.17. Available at: https://www.who.int/maternal_child_adolescent/documents/women-deliver-global-strategy/ru/(access: 05.05.2017.)

2. Aminova A. I., Minchenko E. Iu. [Causes of chronic gastrodudenal and bone disorder development in children living under the effect of human induced ecological factors (literature review)]. Eksp Klin Gastroenterol. 2014;(1):95-101. Russian. PMID: 25518463.

3. Lazebnik L. B., Alexeenko S. A., Lyalukova E. A., et al. Recommendations on management of primary care patients with symptoms of dyspepsia. Experimental and Clinical Gastroenterology. 2018;(5):4-18. (In Russ.)

4. Lyamets L. L., Evseev A. V., Danilov A. I. Method for making statistical decisions about conditions caused by pharmacological exposure based on the minimum average risk criterion. Vestnik of the Smolensk State Medical Academy. 2020;2:50-60. (in Russ.) doi: 10.37903/vsgma.2020:2.7.

5. Turdieva S. T., Ganieva D. K., Abdurashidova Kh. B. Chronic gastroduodenal pathology in schoolchildren: the clinical picture and features of the course. Experimental and Clinical Gastroenterology. 2021;1(1):111-117. (In Russ.) doi: 10.31146/1682-8658-ecg-185-1-111-117.

6. Korobeynikova E. R., Shkatova E. Yu. The health status of recruits with gastroduodenal erosion. Vyatskiy meditsinskiy vestnik. (Vyatka Bulletin of Medical). 2017; 3 (55): 57-62. (In Russ.)

7. Rychkova L. V., Pogodina A. V., Ayurova Z. G., Klimkina J. N. Obesity and health-related quality of life in adolescents from ethnic groups of rural areas of Buryatia, Russia. Bulletin of Siberian Medicine. 2018;17(3):105-114. (In Russ.) doi: 10.20538/1682-0363-2018-3-105-114.

8. Yang Yu, Shengtao Zhu, Peng Li, Li Min, Shutian Zhang. Helicobacter pylori infection and inflammatory bowel disease: a crosstalk between upper and lower digestive tract. Cell Death Dis. 2018 Oct.; 9(10): 961. doi: 10.1038/s41419-018-0982-2.

9. Turdieva S. T. Effect of enteric oxygen therapy on helicobacteriosis in the rehabilitation of children with chronic gastroduodenal pathology. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2018;63(4):69-72. (In Russ.) doi: 10.21508/1027-4065-2018-63-4-69-72.

10. Fisher L., Fisher A., Smith P. N. Helicobacter pylori Related Diseases and Osteoporotic Fractures (Narrative Review). J Clin Med. 2020;9(10):3253. doi: 10.3390/jcm9103253.

11. Pensabene L., Salvatore S., D’Auria E., et al. Cow’s Milk Protein Allergy in Infancy: A Risk Factor for Functional Gastrointestinal Disorders in Children?. Nutrients. 2018;10(11):1716. doi:10.3390/nu10111716.

12. Mărginean MO, Mărginean CO, Meliţ LE, Voidăzan S, Moldovan V, Bănescu C. The impact of host’s genetic susceptibility on Helicobacter pylori infection in children. Medicine (Baltimore). 2017;96(30): e7612. doi:10.1097/MD.0000000000007612.

13. Ageeva E. S., Shtygasheva O. V., Ryazantseva N. V., Kharkov V. N., Stepanov V. A. The etno-population features of IL-1 β gene polimorfism distribution at Helicobacter pylori-associated gastroduodenal pathology. Bulletin of Siberian Medicine. 2011;10(3):14-18. (In Russ.) doi: 10.20538/1682-0363-2011-3-14-18.


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For citations:


Turdieva Sh.T. The premorbid background and the most significant predictors of the development chronic gastroduodenal pathology in children. Experimental and Clinical Gastroenterology. 2021;(9):78-85. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-193-9-78-85

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