A case of curative surgical treatment of the rare pancreatic tumor in a child

Pancreatic tumors are very rare problem in children that mostly in literature presented just with case reports. Solid-pseudopapillary tumors of the pancreas are a little part, just about 1–2%, from all nonendocrine tumors of the pancreas. About 90% of all patients with this tumor are female teenagers and young women. Solid-pseudopapillary tumors of the pancreas are innocent, and mostly all of them are incidental findings. However, we can see clinical findings if patient has big size of such tumor, which compress nearest anatomical structures. In this article we present a case of incidental finding of solid- pseudopapillary tumor of body and tale of the pancreas in 11 years old girl, who was treated with distal resection of pancreas.

1. Zhou H., Cheng W., Lam K. Y., Chan Godfrey C. F., Khong P. L. Tam Paul K. H. Solid-cystic papillary tumor of the pancreas in children. Pediatric surgery international. 2001; 17(8): 614–620. DOI: 10.1007/s003830100005.

2. Ismail-zade R.S., Kotchubinsky D. V., Khalafova L. P., Aleskerova G. A., Akhadova N. A., Osmanov Sh. Sh. Pancreatoblastoma in Children. Onkopediatriya. 2016; 3(3): 214–221. DOI: 10.15690/onco.v3i3.1600. (In Russian).

3. Sokolov Y.Y., Stonogin S. V., Donskoy D. V., Povarnin O. Y., Vilesov A. V. Laparoscopic pancreatic resections for solid pseudopapillary tumor in children. European journal of pediatric surgery. 2009; 19 (06): 399–401. DOI: 10.1055/s-0029–1237356.

4. Rebhandl W., Felberbauer F. X., Puig S., et al. Solidpseudopapillary tumor of the pancreas (Frantz tumor) in children: Report of four cases and review of the literature. Journal of surgical oncology. 2001; 76 (4): 289–296. DOI: 10.1002/jso.1048.

5. Sokolova I.N, Smirnova Е. А., Delektorskaya V. V., et al. Solid-pseudopapillary neoplasm of the pancreas: a clinico-pathological study of 39 cases. Vestnik RONTC im. N. N. Blokhina. 2016; 27 (2): 67–74. (In Russian).

6. Dall’Igna P., Cecchetto G., Bisogno G., et al. Pancreatic tumors in children and adolescents: the Italian TREP project experience. Pediatric blood & cancer. 2010; 54 (5): 675–680. DOI: 10.1002/pbc.22385.

7. Leraas H.J., Kim J., Sun, Z., et al. Solid pseudopapillary neoplasm of the pancreas in children and adults: A national study of 369 patients. Journal of pediatric hematology/oncology. 2018; 40 (4): 233–236. DOI: https://doi.org/10.1097/MPH.0000000000001049.

8. Hsieh L., Burjonrappa S. Pediatric pancreatic tumors: a review of current concepts. J Pancreas (Online). 2016; 17 (3): 257–262.

9. Mylonas K.S., Nasioudis D., Tsilimigras D. I., Doulamis I. P., Masiakos P. T., Kelleher C. M. A population- based analysis of a rare oncologic entity: Malignant pancreatic tumors in children. Journal of pediatric surgery. 2018; 53 (4): 647–652. DOI: https://doi.org/10.1016/j.jpedsurg.2017.06.024.

10. Pinsky S.B., Beloborodov V. A., Batoroev J. K., Dvornichenko V. V. Neuroendocrinniye opukholi podzheludochnoy zhelezy. Sibirsky medicinsky journal (Irkutsk). 2013; 120 (5): 12–16. (In Russian).

11. Chung E.M., Travis M. D., Conran R. M. Pancreatic tumors in children: radiologic- pathologic correlation. Radiographics. 2006; 26 (4): 1211–1238. DOI: 10.1148/rg.264065012.

12. Stepanova Yu.A., Karmazanovsky G. G., Kubyshkin V. A., Shchegolev A. I. Rare cystic masses of the pancreas: differential radiological diagnosis. Ukrainian Journal of Surgery. 2013; 3 (22): 99–115. (In Russian).

13. Shabunin A.V., Tavobilov M. M., Paklina O. V., et al. Solid pseudopapillary tumor of the pancreas in a man: a case report. Siberian Journal of Oncology. 2019; 18 (5): 113–117. DOI: 10.21294/1814–4861–2019–18–5–113–117. (In Russian).

14. Tursunov K.T., Myrzakhmet A. S., Yakovidi- Koneva A.S., Mamyrasyl A. M., Abdrakhmanov D. S. Complications of solid pseudopapillary pancreatic tumors. Russian journal of pediatric surgery, anesthesia and intensive care. 2019; 9 (2): 91–96. DOI: 10.30946/2219–4061–2019–9–2–91–96. (In Russian).

15. Gordienko E.N., Pakhlinа O. V., Chekmareva I. A., Rothin D. L., Gorin D. S. MYC family genes in solidpseudopapillary tumors of the pancreas. Rossiiskiy medico- biologicheskiy vestnik imeni akademika I. P. Pavlova. 2013; 2: 13–20. (In Russian).

16. Paklina O.V., Gordienko E. N., Chekmareva I. A. Histogenesis of solid- pseudopapillary tumor of a pancreas. Kletochnaya transplantologiya i tkanevaya injeneriya. 2013; 8 (2): 63–67. (In Russian).

17. Vetsheva N.N., Karmazanovsky G. G. Differential diagnosis of solid pseudopapillary tumors of the pancreas. Journal of Experimental and Clinical Surgery. 2018; 6 (2): 40–47. DOI: 10.24411/2308–1198–2018–12005. (In Russian).

18. Chkhikvadze V.D., Zelenina I. A., Akhaladze G. G. Solid Pseudopapillary Pancreatic Tumor, Problems of Diagnostics and Treatment. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2018; 20 (1): 106–115. DOI: 10.16931/1995–5464.20151106–115. (In Russian).

19. Nasher O., Hall N. J., Sebire N. J., De Coppi P., Pierro A. Pancreatic tumours in children: diagnosis, treatment and outcome. Pediatric surgery international. 2015; 31 (9): 831–835. DOI: https://doi.org/10.1007/s00383–015–3727–7.

20. Kozlova L.E., Turova S. V., Botoeva M. S., Konotopceva A. N. Ultrasound case of solid pseudopapillary tumor of the pancreas. Acta Biomedica Scientifica. 2016; 1 (3–1 (109)). (In Russian).

21. Słowik- Moczydłowska, Ż., Gogolewski, M., Yaqoub, S., Piotrowska, A., & Kamiński, A. Solid pseudopapillary tumor of the pancreas (Frantz’s tumor): two case reports and a review of the literature. Journal of medical case reports. 2015: 9(1): 268. DOI: 10.1186/s13256–015–0752-z.

22. Ryabin N.S., Katrich A. N., Bykov M. I., Stash R. G. Th e possibilities of endoscopic ultrasonography in the diagnostics of solid pancreatic neoplasms. Kubanskij nauchnyj medicinskij vestnik. 2018; 25 (6): 177–183. DOI: 10.25207 / 1608–6228–2018–25–6–177–183. (In Russian).

23. Kerimov PA, Kazantsev AP, Rubansky MA, et al. Solid Pseudopapillary Pancreatic Tumors in Pediatric Patients: Literature Review. Onkopediatria. 2016; 3 (4): 288–291. DOI: 10.15690/onco.v3i4.1632. (In Russian).

24. Crocoli A., Grimaldi C., Virgone C., et al. Outcome after surgery for solid pseudopapillary pancreatic tumors in children: Report from the TREP project – Italian Rare Tumors Study Group. Pediatric blood & cancer. 2019; 66 (3): e27519. DOI: 10.1002/pbc.27519.

25. Branco C., Vilaca S., Falcao J. Solid pseudopapillary neoplasm–Case report of a rare pancreatic tumor. International journal of surgery case reports. 2017; 33: 148–150. DOI: 10.1016/j.ijscr.2017.02.049.

26. Meshikhes A.W., Atassi R. Pancreatic pseudopapillary tumor in a male child. JOP. 2004; 5 (6): 505–511.

27. Dronov O.I., Dronov V. L., Roschyna L. O., Mokryk O. M. Single clinical observations pseudopapillary solid neoplasms of the pancreas in pregnant women. Zdorov’e zhenshchiny. 2017; 4: 11–15. (In Russian).

28. Komissarov I.A., Peredereev S. S., Komissarov M. I. Solidno- psevdopapillyarnaya opuhol’ podzheludochnoj zhelezy u devochki 15 let. Detskaya hirurgiya. 2012; 2: 53. (In Russian).

29. Kriger A.G., Berelavichus S. V., Gorin D. S., Polaykov I. S. Robot-assisted surgeries for solid pseudopapillary tumors of the pancreas (literary reference and clinical observation). Journal of Experimental and Clinical Surgery. 2012; 5 (4): 691–698. (In Russian).

30. Makeeva- Malinovskaja N. Ju., Karmazanovsky G. G., Kochatkov A. V., Karelskaja N. A. Modern aspects of CT visualization and differential diagnosis of neuroendocrine neoplasia of pancreas. Medicinskaya vizualizaciya. 2012; 5: 40–50. (In Russian).

31. Halin K.D., Agapov M.YU., Zvereva L. V., SHul’ga I.V., Vishnevskaya A. N., Dvojnikova E. R., Bobkov A. V. Solid Pseudopapillary Pancreatic Tumor – Case Study and Literature Review. Eksp Klin Gastroenterol. 2016;(4):90–93. (In Russian).

32. Shchepotin I.B., Lukashenko A. V., Kolesnik E. A., Prijmak V. V., ZHukov YU.A., Burlaka A. A., Ganich A. V. Features of performing pancreatoduodenal resection in children. Klinicheskaya onkologiya. 2013; 4 (15): 6–15. (In Russian).

33. Razumovskij A.YU., Alhasov M. B., Mitupov Z. B., et al. Demonstraciya: «Laparoskopicheskoe udalenie solidnoj psevdopapillyarnoj opuholi podzheludochnoj zhelezy». [Demonstration: “Laparoscopic removal of a solid pseudopapillary tumor of the pancreas”]. Rossijskij vestnik detskoj hirurgii, anesteziologii i reanimatologii. 2015; 5 (2): 111–114. (In Russian).

34. Esposito C., De Lagausie P., Escolino M., et al. Laparoscopic resection of pancreatic tumors in children: results of a multicentric survey. Journal of Laparoendoscopic & Advanced Surgical Techniques. 2017; 27 (5): 533–538. DOI: https://doi.org/10.1089/lap.2016.0630.

35. Yang F., Yu X., Bao Y., Du Z., Jin C., Fu D. Prognostic value of Ki-67 in solid pseudopapillary tumor of the pancreas: Huashan experience and systematic review of the literature. Surgery. 2016; 159 (4): 1023–1031. DOI: https://doi.org/10.1016/j.surg.2015.10.018.

36. Koshel A.P., Klokov S. S., Popov K. M., et al. Solidpseudopapillar neoplasm of the pancreas in a young woman: a clinical case. Sibirskij onkologičeskij žurnal. 2016; 15 (3): 102–107. DOI: 10.21294/1814–4861–2016–15–3–102–109. (In Russian).

37. Ismail-zade R.S., Melikov R. N., Mamedov Yu.N., et al. Solid Pseudopapillary Tumor of the Pancreas in Children. Onkopediatria. 2017; 4 (3): 192–198. DOI: 10.15690/onco.v4i3.1750. (In Russian).