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Experimental and Clinical Gastroenterology

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Change in concentration of ammonia and other biochemical indicators in patients with new coronaviral infection

https://doi.org/10.31146/1682-8658-ecg-188-4-76-83

Abstract

The article demonstrates the results of a study to study the comparative assessment of the concentration of ammonia in the peripheral blood of patients with a viral infection of COVID-19 against the background of previously existing hepatic pathology and without it. There was a correlation between peripheral blood hyperammonemia and an increase in the concentration of markers of acute inflammation. The relationship between a high degree of hyperammonemia and a severe course / death as a result of the development of a new coronavirus infection in the studied patients was traced. The role of the initial chronic hepatic pathology (including non-alcoholic fatty liver disease) as a factor in the unfavorable course of the new coronavirus infection is highlighted.

About the Authors

L. B. Lazebnik
Federal State Budgetary Educational Institution of Higher Education “Moscow State University of Medicine and Dentistry named after A. I. Evdokimov” Ministry of Health of the Russian Federation
Russian Federation

Leonid B. Lazebnik, Professor of the Department of Polyclinic Therapy, Professor, Doctor of Medical Sciences

127994, GSP-4, Moscow, Rakhmanovsky lane, 3

Scopus ID: 7005446863



L. V. Tarasova
Federal State Budgetary Educational Institution of Higher Education “Chuvash State University named after I. N. Ulyanov”
Russian Federation

Larisa V. Tarasova, Head of the department of faculty and hospital therapy, Professor, Doctor of Medical Sciences

428015 Russia, Cheboksary, Moskovsky prospect, 45

Scopus ID: 35777248600



E. A. Komarova
Federal State Budgetary Educational Institution of Higher Education “Chuvash State University named after I. N. Ulyanov”
Russian Federation

Еkaterina A. Komarova, post-graduate student of the department of faculty and hospital therapy

428015 Russia, Cheboksary, Moskovsky prospect, 45



Yu. V. Tsyganova
Federal State Budgetary Educational Institution of Higher Education “Chuvash State University named after I. N. Ulyanov”
Russian Federation

Yuliya V. Tsyganova, assistant of the department of faculty and hospital therapy

428015 Russia, Cheboksary, Moskovsky prospect, 45



E. I. Busalaeva
Federal State Budgetary Educational Institution of Higher Education “Chuvash State University named after I. N. Ulyanov”
Russian Federation

Elena I. Busalaeva, Associate Professor of the Department of Faculty and Hospital Therapy

428015 Russia, Cheboksary, Moskovsky prospect, 45

Scopus ID: 56657473200



E. V. Вarsukova
Federal State Budgetary Educational Institution of Higher Education “Chuvash State University named after I. N. Ulyanov”
Russian Federation

Elena V. Вarsukova, Associate Professor of the Department of Faculty and Hospital Therapy

428015 Russia, Cheboksary, Moskovsky prospect, 45



С. F. Oreshnikova
Federal State Budgetary Educational Institution of Higher Education “Chuvash State University named after I. N. Ulyanov”
Russian Federation

Svetlana F. Oreshnikova, Associate Professor of the Department of Faculty and Hospital Therapy

428015 Russia, Cheboksary, Moskovsky prospect, 45



A. V. Oreshnikov
Federal State Budgetary Educational Institution of Higher Education “Chuvash State University named after I. N. Ulyanov”
Russian Federation

Aleksandr V. Oreshnikov, Associate Professor of the Department of Faculty and Hospital Therapy

428015 Russia, Cheboksary, Moskovsky prospect, 45



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Review

For citations:


Lazebnik L.B., Tarasova L.V., Komarova E.A., Tsyganova Yu.V., Busalaeva E.I., Вarsukova E.V., Oreshnikova F., Oreshnikov A.V. Change in concentration of ammonia and other biochemical indicators in patients with new coronaviral infection. Experimental and Clinical Gastroenterology. 2021;(4):76-83. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-188-4-76-83

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