Experience of the use of selective LPS adsorption in complex therapy of gram-negative sepsis
https://doi.org/10.31146/1682-8658-ecg-180-8-83-86
Abstract
A clinical case of successful application of selective extracorporeal endotoxin LPS-adsorption in the complex treatment of severe gram-negative sepsis of obstetric etiology, complicated by systemic multiple organ failure, in late terms was presented.
About the Authors
A. V. Vereshchagin
Perm State Medical University named after Academician E. A. Wagner (PSMU); Perm regional clinic hospital
Russian Federation
Russian Federation
Aleksey V. Vereshchagin - intensive care doctor.
614000, Perm, st. Petropavlovskaya, 26; 614990, Perm, st. Pushkin, 85
L. P. Kotelnikova
Perm State Medical University named after Academician E. A. Wagner (PSMU); Perm regional clinic hospital
Russian Federation
Russian Federation
MD, Professor, head of the Surgical department with the course of Cardiovascular Surgery and Invasive Cardiology.
614000, Perm, st. Petropavlovskaya, 26; 614990, Perm, st. Pushkin, 85
A. V. Nikolenko
Perm State Medical University named after Academician E. A. Wagner (PSMU)
Russian Federation
Russian Federation
Head of the Department of Anesthesiology and Resuscitation.
614000, Perm, st. Petropavlovskaya, 26
A. M. Ponomarev
Perm regional clinic hospital
Russian Federation
Russian Federation
Head of the Department of Resuscitation and Intensive Care.
614990, Perm, st. Pushkin, 85
References
1. Kolesnichenko A. P., Raspopin Y. S., Miller A. A., Belyaev K. Y., Kondrashov M. A. Contemporary approaches то the choice of efferent treatment methods at severe forms of sepsis: a literature review and personal experience. Siberian medical review. 2015; № 6: 36– 42. (In Rus.). DOI 10.20333/25000136–2015–6–36–42
2. Vatazin A. V., Yarustovsky M. B., Fomin A. M. et al. The first experience of using selective hemoperfusion in patients with surgical sepsis. Almanac of Clinical Medicine. 2008;(18):22–29. (In Russ.)
3. Vatazyan A. V., Fomin A. M., Koshelev O. V. et al. Efficiency of selective extracorporeal sorption of gram-negative endotoxin in surgical sepsis. Russian Journal of Transplantology and Artificial Organs. 2008;41(3):40–43. (In Russ.)
4. Sato K., Maekawa H., Sakurada M. et al. Direct hemoper-fusion with polymyxin B immobilized fi ber fоr abdominal sepsis in Europe. Surg Today. 2011;41(6):754–760.
5. Lipcsey M., Tenhunen J., Pischke S. E. et al. Endotoxin removal in septic chock with Alteco LPS adsorberwas safe but showed no benefit compared to placebo in the double-blind randomized controlled trial – the asset study. 2019. Dec 26. doi:10.1097/SHK.0000000000001503.
6. Yarustovsky M. B., Abramyan M. V., Popok Z. V. et al. The first experience of using selective sorbents in complex intensive care of infectious and septic complications in patients after cardiac surgery. Anesthesiology and Reanimatology. 2008, No. 6, pp. 49–55.
7. Cruz D. N., Perazella M. F., Bellomo R. et al. Effectiveness of polymyxin B-immobilised fiber colomn in sepsis: a systematic review. Crit Care. 2007, no.11, R47.
8. Zhou F., Peng Z., Murugan R., Kellum J. A. Blood purification and mortality in sepsis: a metaanalysisof randomized trials. Crit Care Med. 2013;41(9):2209–2220.
Review
For citations:
Vereshchagin A.V., Kotelnikova L.P., Nikolenko A.V., Ponomarev A.M. Experience of the use of selective LPS adsorption in complex therapy of gram-negative sepsis. Experimental and Clinical Gastroenterology. 2020;(8):83-86. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-180-8-83-86
Views:
315
Email this article 