Morbidity, mortality and case fatality rate from liver cirrhosis in the age aspect in Kyrgyzstan for the period 2010–2017

The purpose is to study the dynamics of morbidity, mortality and case fatality ratefrom liver cirrhosis in the age aspect from 2010–2017 in Kyrgyzstan.

Materials and methods: Analyzed state reporting forms No. 12 “Report on morbidity and preventive work (family medicine center, dispensary)” and “C51 — Distribution of deaths by sex, age groups and causes of death” from 2010–2017. Data processed by Microsoft Office Excel.

Results: The average cumulative prevalence of liver cirrhosis (K 74) in persons older than 15 years for the period 2010–2017 was 50.9 0/0000, the average incidence is 12.3 0/0000, the mortality is 45.2 0/0000. Persons over 75 years old had the highest mortality rate — 160, 7 0/0000, the age group “45–59 years old” occupied the third position (92.8 0/0000) after the persons “60–74 years old” (140.9 0/0000). It is necessary to emphasize the presence of mortality among children and individuals 15–24 years old, although the incidence rates (0.2 0/0000 and 2.5 0/0000, respectively) and the  proportion (0.2 % and 1.6 %, respectively) were low. In the period 2015–2017 were registered 47 children with “K 74”, of which 15 were fi rst identifi ed, and for 2011–2017 yy. 32 children with a fatal outcome. Over the past 3 years there has been a tendency for the growth of all three indicators in children. For 2010–2017 yy. the average cumulative case fatality ratein persons over 15 years of age prevailed over children in 2,069.9 cases per 10,000 patients (8878.4 0/000 and 6808.5 0/000, respectively). The case fatality rateamong adults decreased 1.6 times (11176.8 0/000 and 6815.2 0/000, 2010 and 2017, respectively), and among children 1.5 times(4285.7 0/000 and 2857.1 0/000, 2015 and 2017, respectively).

Conclusion: On the basis of the obtained data, in order to improve the K 74 accounting system, an emergency notifi cation (Form No. 58u) was introduced in the country for newly detected and lethal cases of cirrhosis and liver cancer in the outcome of hepatitis B and C. To develop specifi c prevention measures and control strategies in general, the country needs a register of patients with cirrhosis and liver cancer with etiological interpretation.

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