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Effect of l-ornithine-l-aspartate therapy on the hyperammonemia level and results of the number connection test of patients suffering from nonalcoholic fatty liver disease

https://doi.org/10.31146/1682-8658-ecg-169-9-80-84

Abstract

The aim was to study the hyperammonemia level and the duration of implementation of the number connection test (NCT) for patients with nonalcoholic fatty liver disease (NAFLD) in the pre-cirrhosis stage, including effect of the oral administration of L-ornithine-L-aspartate (LOLA) on these indices, and NCT correlation with body chemistry values. Material and methods: the research covered 103 patients with NAFLD to study the hyperammonemia level and other relevant blood chemistry values; we performed NCT before and after the LOLA treatment. The aim was to study the hyperammonemia level and the duration of implementation of the number connection test (NCT) for patients with nonalcoholic fatty liver disease (NAFLD) in the pre-cirrhosis stage, including effect of the oral administration of L-ornithine-L-aspartate (LOLA) on these indices, and NCT correlation with body chemistry values. Material and methods: the research covered 103 patients with NAFLD to study the hyperammonemia level and other relevant blood chemistry values; we performed NCT before and after the LOLA treatment.

About the Authors

E. A. Kizova
City Clinical Hospital № 13 of Avtozavodsky region of Nizhny Novgorod
Russian Federation
Elena A. Kizova, Head of the Gastroenterology Department, Ph. D.


Yu. P. Potekhina
Privolzhsky research medical university
Russian Federation
Yuliya P. Potekhina, Department of Normal Physiology n. a. N. Yu. Belenkov, Professor, D. Sci.


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Review

For citations:


Kizova E.A., Potekhina Yu.P. Effect of l-ornithine-l-aspartate therapy on the hyperammonemia level and results of the number connection test of patients suffering from nonalcoholic fatty liver disease. Experimental and Clinical Gastroenterology. 2019;(9):80-84. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-169-9-80-84

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