Russian Consensus “Hyperammonemia in Adults”
https://doi.org/10.31146/1682-8658-ecg-172-12-4-23
Abstract
The human body, like any other, is an intermediate component of the nitrogen cycle in nature. Consuming nitrogen from the external environment in the form of various compounds, the body processes it into ammonia - one of the final products of exchange of nitrogen-containing substances [1], which is removed from the body in the form of urea. The most active ammonia producers are organs with high exchange of amino acids and biogenic amines - nerve tissue, liver, intestine, and muscles. In a state of nitrogen equilibrium, the adult body consumes and releases about 15 g of nitrogen per day, temporary or permanent disruption of nitrogen balance results in a great number of physiological conditions and diseases, and the need to stabilize it is well known. However, despite a huge number of studies on the role of nitrogen metabolism and its compounds in the clinic, to date we have not been able to find any conciliation document in the world literature on the classification of ammonia-ammonium levels in human blood and approaches to the correction of hyperammonemia, which was the basis for the emergence of this consensus.
About the Authors
L. B. Lazebnik
Moscow State University of Medicine and Dentistry named after A. I. Evdokimov
Russian Federation
Russian Federation
E. V. Golovanova
Moscow State University of Medicine and Dentistry named after A. I. Evdokimov
Russian Federation
Russian Federation
S. A. Alekseenko
Far-Eastern State Medical University
Russian Federation
Russian Federation
A. O. Bueverov
The State Education Institution of Higher Professional Training The First Sechenov Moscow State Medical University under Ministry of Health of the Russian Federation; The State Budgetary Healthcare Institution of Moscow Area Moscow regional research clinical institute n. a. M. F. Vladimirskiy
Russian Federation
Russian Federation
E. Yu. Plotnikova
Kemerovo State Medical Academy under Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
A. I. Dolgushina
Federal State Budgetary Educational Institution of Higher Education “South-Ural State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
L. Yu. Ilchenko
The Russian National Research Medical University named after N. I. Pirogov
Russian Federation
Russian Federation
T. V. Ermolova
North-Western State Medical University named after I. I. Mechnikov
Russian Federation
Russian Federation
L. V. Tarasova
Medical Institute of Surgut State University; Chuvash State University
Russian Federation
Russian Federation
E. D. Lee
Bank of Russia Medical Center
Russian Federation
Russian Federation
Yu. V. Tsyganova
Chuvash State University
Russian Federation
Russian Federation
V. A. Akhmedov
Federal State Funded Educational Institution for Higher Education Omsk State Medical University of the Ministry of Public Health of the Russian Federation
Russian Federation
Russian Federation
E. A. Ageeva
KHSBI “City Clinical Polyclinic № 3”
Russian Federation
Russian Federation
V. M. Losev
Samara State Medical University
Russian Federation
Russian Federation
I. N. Kupriyanova
Ural State Medical University
Russian Federation
Russian Federation
S. N. Serikova
Regional Clinical Hospital № 2
Russian Federation
Russian Federation
N. V. Korochanskaya
Regional Clinical Hospital № 2
Russian Federation
Russian Federation
L. G. Vologzhanina
Perm State Medical University named after E. A. Wagner
Russian Federation
Russian Federation
Ya. S. Zimmerman
Perm State Medical University named after E. A. Wagner
Russian Federation
Russian Federation
E. I. Sas
Military Medical Academy named after S. M. Kirov of the Ministry of Defence of the Russian Federation
Russian Federation
Russian Federation
S. V. Zhuravel
Moscow State University of Medicine and Dentistry named after A. I. Evdokimov
Russian Federation
Russian Federation
S. V. Okovity
St. Petersburg State Chemical and Pharmaceutical Academy
Russian Federation
Russian Federation
M. F. Osipenko
Novosibirsk State Medical University
Russian Federation
Russian Federation
V. G. Radchenko
Military Medical Academy named after S. M. Kirov of the Ministry of Defence of the Russian Federation
Russian Federation
Russian Federation
G. S. Soldatova
Novosibirsk State University Akademgorodok
Russian Federation
Russian Federation
S. I. Sitkin
North-Western State Medical University named after I. I. Mechnikov; Federal Medical and Biological Agency “State Research Institute of Highly Pure Biopreparations”
Russian Federation
Russian Federation
P. V. Seliverstov
North-Western State Medical University named after I. I. Mechnikov
Russian Federation
Russian Federation
G. V. Shavkuta
Rostov State Medical University of the Ministry of Health of Russia
Russian Federation
Russian Federation
E. N. Butova
Rostov State Medical University of the Ministry of Health of Russia
Russian Federation
Russian Federation
S. A. Kozhevnikova
Voronezh State Medical University named after N. N. Burdenko
Russian Federation
Russian Federation
Review
For citations:
Lazebnik L.B., Golovanova E.V., Alekseenko S.A., Bueverov A.O., Plotnikova E.Yu., Dolgushina A.I., Ilchenko L.Yu., Ermolova T.V., Tarasova L.V., Lee E.D., Tsyganova Yu.V., Akhmedov V.A., Ageeva E.A., Losev V.M., Kupriyanova I.N., Serikova S.N., Korochanskaya N.V., Vologzhanina L.G., Zimmerman Ya.S., Sas E.I., Zhuravel S.V., Okovity S.V., Osipenko M.F., Radchenko V.G., Soldatova G.S., Sitkin S.I., Seliverstov P.V., Shavkuta G.V., Butova E.N., Kozhevnikova S.A. Russian Consensus “Hyperammonemia in Adults”. Experimental and Clinical Gastroenterology. 2019;(12):4-23. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-172-12-4-23
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