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Efficiency and safety of opioid therapy of chronic pain syndrome in patients with cancer of the refractory iron: clinico-pathogenetic features

https://doi.org/10.31146/1682-8658-ecg-170-10-45-51

Abstract

Aim. To study the influence of clinical and pathogenetic factors in patients with pancreatic cancer on the efficacy and safety of analgesic therapy of chronic pain syndrome.

Materials and methods. Clinical features of formation of chronic pain syndrome predetermining the efficacy and safety of analgesic therapy were studied in 82 patients with pancreatic cancer.

Results. The efficacy and safety of opioids in the comparison groups of morphine sulfate, fentanyl TTC and oxycodone / naloxone in patients with pancreatic cancer was shown.

About the Authors

O. P. Bobrova
Krasnoyarsk State Medical University; Krasnoyarsk Regional Cancer Centre
Russian Federation


N. A. Schneider
National Medical Research Center of Psychiatry and Neurology
Russian Federation


M. M. Petrova
Krasnoyarsk State Medical University
Russian Federation


D. V. Dmitrenko
Krasnoyarsk State Medical University
Russian Federation


S. K. Zyryanov
Peoples’ Friendship University of Russia
Russian Federation


S. N. Zobova
Krasnoyarsk State Medical University; Federal Research Center “Krasnoyarsk Scientific Center Siberian Branch of the Russian Academy of Sciences”
Russian Federation


References

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Review

For citations:


Bobrova O.P., Schneider N.A., Petrova M.M., Dmitrenko D.V., Zyryanov S.K., Zobova S.N. Efficiency and safety of opioid therapy of chronic pain syndrome in patients with cancer of the refractory iron: clinico-pathogenetic features. Experimental and Clinical Gastroenterology. 2019;1(10):45-51. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-170-10-45-51

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