Preview

Experimental and Clinical Gastroenterology

Advanced search

Role of normal intestinal microflora (microbiotas) in rehabilitation of patients with obesity

https://doi.org/10.31146/1682-8658-ecg-165-5-105-110

Abstract

Today there are many proofs that the microbiota can have an impact on organism owner body weight, increasing efficiency of extraction of energy from the absorbed food, first of all - from polysaccharides. During too time and a dietotherapy considerably affects structure of a microbiota, for example, the diet with the high content of fats can change structure of bacteria in intestines. It is known that at identical consumption of food and the mode of exercise stresses the different susceptibility to increase or decrease in body weight is noted. As the reason serves various metabolic activity of a microbiome of the person, including various composition of intestinal microflora. Influence of intestinal microflora on development of atherosclerosis, obesity, the metabolic syndrome (MS) is proved, diabetes mellitus (DM), non-alcoholic fatty liver disease (NAFLD), irritable bowel syndrome (IBS). The research objective consisted in normalization of intestinal microflora of patients with obesity for optimization of process of a dietotherapy and rehabilitation in general. The research was conducted in two large networks fitness of downtowns of St. Petersburg and in the center of recovery medicine and correction of weight of medical holding of “Physician” (base of department of physiotherapy exercises and sports medicine of SEI VPO to SZGM by it I. I. Mechnikov) with the 2016-2018th. Three hundred patients 180 (60%) women and 120 (40%) men with the diagnosis the excess body weight (preobesity) (BMI> 24.99) and obesity (BMI> 29.99) (the recommendations of WHO of 1997) were divided into two groups - the main and control. To each of the examined patients the analysis a calla on an intestinal dysbiosis with sensitivity to bacteriophages was made. As a result of a research significant decrease in own microflora (86.45%) of intestines of patients of the significant bacteria (32.56%) having obesity and also growth existence etiologically was revealed. For normalization of intestinal microflora drugs of the following groups were used: adsorbents; means the normalizing microflora, in combinations; antidiarrheal means; bakteritofag. After the carried-out therapy on normalization of intestinal microflora on the scheme offered by us in combination with rehabilitation actions decrease in symptoms of a metabolic syndrome, diabetes mellitus, NAFLD, IBS and also reduction of terms of rehabilitation in the main group (28.56%) was noted. In this regard as the perspective direction of prevention of metabolic disturbances at patients with obesity use of the scheme of normalization of intestinal microflora offered by us can be considered.

About the Authors

D. N. Bobunov
North-Western State Medical University named after I. I. Mechnikov, Ministry of Health of Russian Federation
Russian Federation


A. K. Iordanishvili
North-Western State Medical University named after I. I. Mechnikov, Ministry of Health of Russian Federation
Russian Federation


V. D. Mikhailov
North-Western State Medical University named after I. I. Mechnikov, Ministry of Health of Russian Federation
Russian Federation


O. N. Shapurko
North-Western State Medical University named after I. I. Mechnikov, Ministry of Health of Russian Federation
Russian Federation


Review

For citations:


Bobunov D.N., Iordanishvili A.K., Mikhailov V.D., Shapurko O.N. Role of normal intestinal microflora (microbiotas) in rehabilitation of patients with obesity. Experimental and Clinical Gastroenterology. 2019;(5):105-110. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-165-5-105-110

Views: 280


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1682-8658 (Print)