Clinical features, nutrition and prevention of gallstone disease in combination with metabolic syndrome in women

Abstract

The aim is to identify the characteristics of nutrition and their relationship with gastrointestinal symptoms in women with Gallstone Disease (GSD) with metabolic syndrome (MS). The open clinical study “series of cases” included 97 patients with GSD: group 1 - GSD with MS (n=67), group 2 - with GSD without MS (n=30), comparable in age and BMI. Criteria for MS - NCEP ATP-III, 2001. A nutritional frequency questionnaire validated at the Institute of Nutrition RAS was used. Results. In group 1, significantly less vegetable proteins (22.6 ± 1.2) and fats (29.7 ± 2.0), total carbohydrates (161.6 ± 8.5), and sugar (74.1 ± 4,5) and fibers (27.9 ± 1.7 g/day) than in group 2 (26.2 ± 1.7, 38.8 ± 3.7, 194.7 ± 15.6, 107.3 ± 12.2, 43.1 ± 6.4 g/day, respectively). In group 1, significantly more animal proteins (56.8 ± 2.4 g/day) and cholesterol (223.6 ± 12.0 mg/day) were consumed than in group 2 (45.5 ± 3.2 g/day and 188.8 ± 21.6 mg/day, p<0.05). Association between the animal fats and proteins consumption with pain and dyspeptic symptoms was stronger in group 1 than in group 2. Conclusion. Women with GSD and MS consumed less vegetable foods and more animal food, which were accompanied by an increase in gastrointestinal symptoms of gallstones.