Gastroesophageal reflux disease with non-esophageal manifestations, the formation of Barrett’s esophagus on the background of a hiatal hernia
          
      
    
      
    
                        
          
    
  
      
  
    
                
            Abstract
            Over the years, Barrett’s esophagus doesn`t lose its relevance to clinicians and researchers. The problem is acute as the disease is considered as a precancerous condition associated with the risk of adenocarcinoma in the lower third of the esophagus. Knowledge of non-esophageal clinical “masks” of gastroesophageal reflux disease (GERD) and timely diagnosis is extremely relevant for Barrett’s esophagus patients with a high risk of its development as well as complex treatment and dynamic observation of these patients. The article describes a clinical case of a 10-year unsuccessful case of a 36-years old man with GERD complicated by Barrett’s esophagus. Different specialists who observed the patient didn`t evaluate patient’s cardiac and otorhinolaryngological complaints as extra-esophageal “masks” of GERD, although there was a bright clinical picture of the disease, repeated instrumental examination, including esophagogastroduodenoscopy. courses of antioxidants, metabolic drugs, vegetocorrectors, local treatment of laryngitis, intraperitoneal instillations were unjustifiably prescribed. This practice underlines the timeless relevance of assessing anamnestic data, clarifying the presence of comorbid conditions to ensure an adequate personalized drug approach.
         
              
        
                        		
                     
    
      
                  About the Authors
              
               
             O. V. Tsygankova
         
        
                        Novosibirsk State Medical University, Ministry of Health of Russia; Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Science
        
Russian Federation
    
				    
    
    
             
             L. D. Latyntseva
         
        
                        Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Science
        
Russian Federation
    
				    
    
    
             
             T. I. Batluk
         
        
                        Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Science
        
Russian Federation
    
				    
    
    
             
             T. K. Gaskina
         
        
                        Novosibirsk Regional Clinical Diagnostic Center
        
Russian Federation
    
				    
    
    
             
             A. A. Starichkov
         
        
                        Novosibirsk State Medical University, Ministry of Health of Russia
        
Russian Federation
    
				    
    
    
             
             A. O. Bueverov
         
        
                        First Moscow State Medical University named after I. M. Sechenov; Moscow Regional Research and Clinical Institute (“MONIKI”)
        
Russian Federation
    
				    
    
    
          
     
        
    
    
    
 
    
      For citations:
                                    Tsygankova O.V., 
                                Latyntseva L.D., 
                                Batluk T.I., 
                                Gaskina T.K., 
                                Starichkov A.A., 
                                Bueverov A.O.
                                              Gastroesophageal reflux disease with non-esophageal manifestations, the formation of Barrett’s esophagus on the background of a hiatal hernia.      Experimental and Clinical Gastroenterology.            2019;(3):16-23.  
                                                                                                      (In Russ.)
                                          
                                                          
    
  
  
  
  
    
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