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Experimental and Clinical Gastroenterology

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Gastroesophageal reflux disease with non-esophageal manifestations, the formation of Barrett’s esophagus on the background of a hiatal hernia

Abstract

Over the years, Barrett’s esophagus doesn`t lose its relevance to clinicians and researchers. The problem is acute as the disease is considered as a precancerous condition associated with the risk of adenocarcinoma in the lower third of the esophagus. Knowledge of non-esophageal clinical “masks” of gastroesophageal reflux disease (GERD) and timely diagnosis is extremely relevant for Barrett’s esophagus patients with a high risk of its development as well as complex treatment and dynamic observation of these patients. The article describes a clinical case of a 10-year unsuccessful case of a 36-years old man with GERD complicated by Barrett’s esophagus. Different specialists who observed the patient didn`t evaluate patient’s cardiac and otorhinolaryngological complaints as extra-esophageal “masks” of GERD, although there was a bright clinical picture of the disease, repeated instrumental examination, including esophagogastroduodenoscopy. courses of antioxidants, metabolic drugs, vegetocorrectors, local treatment of laryngitis, intraperitoneal instillations were unjustifiably prescribed. This practice underlines the timeless relevance of assessing anamnestic data, clarifying the presence of comorbid conditions to ensure an adequate personalized drug approach.

About the Authors

O. V. Tsygankova
Novosibirsk State Medical University, Ministry of Health of Russia; Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Science
Russian Federation


L. D. Latyntseva
Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Science
Russian Federation


T. I. Batluk
Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Science
Russian Federation


T. K. Gaskina
Novosibirsk Regional Clinical Diagnostic Center
Russian Federation


A. A. Starichkov
Novosibirsk State Medical University, Ministry of Health of Russia
Russian Federation


A. O. Bueverov
First Moscow State Medical University named after I. M. Sechenov; Moscow Regional Research and Clinical Institute (“MONIKI”)
Russian Federation


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For citations:


Tsygankova O.V., Latyntseva L.D., Batluk T.I., Gaskina T.K., Starichkov A.A., Bueverov A.O. Gastroesophageal reflux disease with non-esophageal manifestations, the formation of Barrett’s esophagus on the background of a hiatal hernia. Experimental and Clinical Gastroenterology. 2019;(3):16-23. (In Russ.)

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ISSN 1682-8658 (Print)