Variants Of Acid-Breasting Function Of The Stomach In Patients With Connective Tissue Dysplasia

Abstract

Aim. Study of the gastric acid features and acidity variants formation in patients with connective tissue dysplasia. Materials and methods: Gastric acidity variants had selected by Kohonen Self-Organizing Feature Maps. The 24-pH-metry was performed in patients with acid-dependent diseases and connective tissue dysplasia (n=42), patients acid-dependent diseases without connective tissue dysplasia (n=37), patients with connective tissue dysplasia without acid-dependent diseases (n=39), control group (n=36). Results. 1. The 5 gastric acidity variants had selected: hypoacidity, normally, hyperacidity, biliary and reflux. 2. It was detected that biliary and reflux variants diagnosed in patients with acid-dependent diseases and connective tissue dysplasia, hyperacidity variant diagnosed in patients with acid-dependent diseases without connective tissue dysplasia, hypoacidity variant diagnosed in patients with connective tissue dysplasia without acid-dependent diseases (n=39), normally variant diagnosed in control group patients (n=36). Conclusion. The acidity variants described in this study can be used in the work of general practitioner, therapist, gastroenterologist. The symptoms of the connective tissue dysplasia suggests a violation of the acidity so that can improve diagnostic of acid-related diseases in patients with connective tissue dysplasia.