Heartburn In Patients Without Esophagitis. Differential Diagnosis
Abstract
The literature review represents current understanding of the spectrum of disorders, such as non-erosive reflux disease, hypersensitive esophagus and functional heartburn, occurring in the absence of endoscopic data for damage to the mucous membrane of the esophagus and the main symptom of which is heartburn. Particular attention is paid to the importance of differential diagnosis of these disorders, which is carried out using various diagnostic methods and is necessary to choose proper treatment. 24-hour esophageal pH-impedance is the “gold standard” for the diagnosis of patients with heartburn and normal endoscopic picture. The article presents data on the main parameters of daily monitoring, diagnostic criteria that allow to establish the correct diagnosis with high accuracy. The diagnostic capabilities of high-resolution esophageal manometry and therapeutic approaches used in patients with non-erosive reflux disease, hypersensitive esophagus and functional heartburn are also highlighted.
Keywords
изжога,
Римские критерии,
гастроэзофагеальная рефлюксная болезнь,
гиперсенситивный пищевод,
функциональная изжога,
рН-импедансометрия,
манометрия высокого разрешения,
heartburn,
Rome criteria,
gastroesophageal reflux disease,
hypersensitive esophagus,
functional heartburn,
esophageal pH-impedance,
high resolution esophageal manometry
About the Authors
E. V. Barkalova
FSBEI HE “Moscow State Medical and Dental University named after A. I. Evdokimov” of Ministry of Health of Russian Federation
Russian Federation
Russian Federation
Y. A. Kucheryavyy
FSBEI HE “Moscow State Medical and Dental University named after A. I. Evdokimov” of Ministry of Health of Russian Federation
Russian Federation
Russian Federation
M. A. Ovsepian
FSBEI HE “Moscow State Medical and Dental University named after A. I. Evdokimov” of Ministry of Health of Russian Federation
Russian Federation
Russian Federation
I. V. Maev
FSBEI HE “Moscow State Medical and Dental University named after A. I. Evdokimov” of Ministry of Health of Russian Federation
Russian Federation
Russian Federation
D. N. Andreev
FSBEI HE “Moscow State Medical and Dental University named after A. I. Evdokimov” of Ministry of Health of Russian Federation
Russian Federation
Russian Federation
Review
For citations:
Barkalova E.V., Kucheryavyy Y.A., Ovsepian M.A., Maev I.V., Andreev D.N. Heartburn In Patients Without Esophagitis. Differential Diagnosis. Experimental and Clinical Gastroenterology. 2018;(10):74-79. (In Russ.)
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