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Experimental and Clinical Gastroenterology

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Catestatin as a potential diagnostic marker of metabolic syndrome

https://doi.org/10.31146/1682-8658-ecg-235-3-148-151

Abstract

Aim of the study: to evaluate the possibility of using catestatin as a biomarker for the diagnosis of metabolic syndrome. Materials and methods: the study was based on a search for publications mainly over the past 5 years in the PubMed and Google Scholar databases for the keywords “catestatin”, “metabolic syndrome”, “insulin resistance”, “dyslipidemia”. Results: catestatin is a multifunctional peptide that can become a promising tool for the diagnosis of metabolic syndrome. It affects the adrenergic system, reducing sensitivity to catecholamines and causing vasodilation. In addition, catestatin affects the metabolism, reducing the levels of triglycerides and leptin. It also regulates insulin resistance and has an anti-inflammatory effect. Conclusion: catestatin may be a useful tool for the diagnosis and treatment of metabolic syndrome. However, further research is needed to fully understand its role and determine best practices.

About the Authors

D. K. Kuznetsova
Samara State Medical University
Russian Federation


I. V. Gubareva
Samara State Medical University
Russian Federation


A. V. Pashentseva
Samara State Medical University
Russian Federation


References

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Review

For citations:


Kuznetsova D.K., Gubareva I.V., Pashentseva A.V. Catestatin as a potential diagnostic marker of metabolic syndrome. Experimental and Clinical Gastroenterology. 2025;(3):148-151. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-235-3-148-151

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