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Experimental and Clinical Gastroenterology

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Significance of morphological studies in the diagnostics of bilial intraepithelial neoplasia in nonparasitic liver cysts

https://doi.org/10.31146/1682-8658-ecg-214-6-153-156

Abstract

Biliary intraepithelial neoplasia (BilIN) according to modern data is considered as an obligate precancer of the bile ducts. As BILIN progresses, cholangiocarcinoma often develops, characterized by a low five-year survival rate. The aim of this work is to describe the morphological characteristics of BilIN in the epithelium of nonparasitic liver cysts. The material is described after primary and repeated (15) surgical interventions in 99 patients. The morphological manifestations of intraepithelial neoplasia in non-parasitic dysontogenetic liver cysts were studied, their role in the development of liver cholangiocarcinoma was established.

About the Authors

E. V. Gromova
Perm State Medical University n. a. E. A. Wagner of the Ministry of Health of the Russian Federation
Russian Federation


G. G. Freynd
Perm State Medical University n. a. E. A. Wagner of the Ministry of Health of the Russian Federation
Russian Federation


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Review

For citations:


Gromova E.V., Freynd G.G. Significance of morphological studies in the diagnostics of bilial intraepithelial neoplasia in nonparasitic liver cysts. Experimental and Clinical Gastroenterology. 2023;(6):153-156. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-214-6-153-156

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