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Experimental and Clinical Gastroenterology

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Periappendicular changes in patients with ulcerative collitis: overview and clinical observation

https://doi.org/10.31146/1682-8658-ecg-205-9-298-302

Abstract

Ulcerative colitis is inflammatory bowel disease which characterized by inflammation of the colon and rectum: only 20-30% of UC patients have pancolitis, while proctitis and left-sided colon lesions are more common. There is a variant of localization of ulcerative colitis in patients with proctitis and left-sided colon lesion, which changes the rule of continuity of the lesion and is described as an additional periappendicular lesion. The article have been presented the own clinical observation of a patient with distal ulcerative colitis with periappendicular lesion. If a periappendicular lesion have been detected during endoscopy in a typical clinic for distal ulcerative colitis and doubts arise about the correctness of the previously established diagnosis, it is necessary to re-analyze the anamnesis, symptoms, instrumental and histological picture and, taking into account new knowledge about the course of ulcerative colitis in some patients with periappendicular lesion, confirm the initial diagnosis and continue therapy. Such a finding, according to the available literature data, does not require escalation of ulcerative colitis therapy and, as a rule, does not mean the spread of the disease to all parts of the colon.

About the Authors

G. R. Bikbavova
Omsk State Medical University of the Ministry of Healthcare of Russia
Russian Federation


V. A. Akhmedov
Omsk State Medical University of the Ministry of Healthcare of Russia
Russian Federation


S. I. Mozgovoy
Omsk State Medical University of the Ministry of Healthcare of Russia
Russian Federation


L. I. Telyatnikova
Omsk State Medical University of the Ministry of Healthcare of Russia
Russian Federation


E. A. Shmurygina
City clinical hospital № 1 named after A. N. Kabanova
Russian Federation


References

1. Ramos G., Papadakis K. Mechanisms of Disease: Inflammatory Bowel Diseases. Mayo Clin. Proc, 2019;94(1):155-165. doi: 10.1016/j.mayocp.2018.09.013

2. GBD 2017 Inflammatory Bowel Disease Collaborators. The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet Gastroenterol Hepatol, 2020;5(1):17-30. doi: 10.1016/S2468-1253(19)30333-4

3. Dahlhamer J.M., Zammitti E. P., Ward B. W. et al. Prevalence of inflammatory bowel disease among adults aged >/=18 years - United States, 2015. MMWR Morb Mortal Wkly Rep, 2016;65(42):1166-1169. doi: 10.15585/mmwr.mm6542a3

4. Kaistha А., Levine J. Inflammatory bowel disease: the classic gastrointestinal autoimmune disease. Curr Probl Pediatr Adolesc Health Care, 2014;44(11):328-334. doi: 10.1016/j.cppeds.2014.10.003

5. Vatn M.H., Sandvik A. K. Inflammatory bowel disease. Scandinavian Journal of Gastroenterology, 2015;50(6):748-762. doi: 10.3109/00365521.2015.1033000

6. Bager P. Anemia in inflammatory bowel diseases is much more than levels of hemoglobin. Journal of Gastrointestinal and Liver Diseases, 2005;24(2):145-146. doi: 10.15403/jgld.2014.1121.242.aninf

7. Ivashkin V.T., Shelygin Yu.A., Khalif I. L., et al. Clinical guide of russian association of gastroenterology and russian association of coloproctology on diagnostics and treatment of ulcerative colitis. Koloproktologia. 2017;(1):6-30. (In Russ.) @@Ивашкин В. Т., Шелыгин Ю. А., Халиф И. Л. и др. Клинические рекомендации Российской гастроэнтерологической ассоциации и Ассоциации колопроктологов России по диагностике и лечению язвенного колита. Колопроктология. 2017;59(1):6-30.

8. Ivashkin V.T., Shelygin Yu.A., Khalif I. L., et al. Clinical guide of russian association of gastroenterology and russian association of coloproctology on diagnostics and treatment of crohn’s disease. Koloproktologia. 2017;(2):7-29. (In Russ.) doi: 10.33878/2073-7556-2017-0-2-7-29 @@Ивашкин В. Т., Шелыгин Ю. А., Халиф И. Л. и др. Клинические рекомендации Российской гастроэнтерологической ассоциации и Ассоциации колопроктологов России по диагностике и лечению болезни Крона. Колопроктология. 2017;60(2):7-29.

9. Yamagishi N, et al. Clinical and colonoscopic investigation of skipped periappendiceal lesions in ulcerative colitis. Scand J Gastroenterol. 2002;37(2):177-182. doi: 10.1080/003655202753416849.

10. Lumb G., Protheroe R. H. Ulcerative colitis; a pathologic study of 152 surgical specimens. Gastroenterology. 1958;34(3):381-407. doi: 10.1016/S0016-5085(58)80002-5.

11. Cohen T., Pfeffer R. B., Valensi Q. “Ulcerative appendicitis” occurring as a skip lesion in chronic ulcerative colitis; report of a case. Am J Gastroenterol. 1974 Aug;62(2):151-5. PMID: 4855480.

12. Groisman G.M., George J., Harpaz N. Ulcerative appendicitis in universal and nonuniversal ulcerative colitis. Mod Pathol, 1994;7(3):322-325. PMID: 8058703.

13. Ladefoged K. Munck L. K., Jorgensen F., Engel P. Skip inflammation of the appendiceal orifice: a prospective endoscopic study. Scand J Gastroenterol, 2005;40(10):1192-1196. doi: 10.1080/00365520510023305.

14. Matsumoto T., Nakamura S., Shimizu M., et al. Significance of appendiceal involvement in patients with ulcerative colitis. Gastrointest Endosc, 2002;55(2):180-185. doi: 10.1067/mge.2002.121335.

15. Nyboe Andersen N., Gørtz S., Frisch M., et al. Reduce drisk of UC in families affected by appendicitis: a Danish national cohort study. Gut. 2017;66(8):1398-402. doi: 10.1136/gutjnl-2015-311131.

16. Bakman Y., Katz J., Shepela C. Clinical Significance of Isolated Peri-Appendiceal Lesions in Patients With Left Sided Ulcerative Colitis. Gastroenterology Res. 2011;4(2):58-63. doi: 10.4021/gr302w

17. Rubin D.T., Rothe J. A. The peri-appendiceal red patch in ulcerative colitis: review of the University of Chicago experience. Dig Dis Sci. 2010 Dec;55(12):3495-501. doi: 10.1007/s10620-010-1424-x.

18. Langholz E, et al. Changes in extent of ulcerative colitis: a study on the course and prognostic factors. Scand J Gastroenterol. 1996;31(3):260-26.

19. Goldstein N., Dulai M. Contemporary morphologic definition of backwash ileitis in ulcerative colitis and features that distinguish it from Crohn disease. Am J Clin Pathol. 2006 Sep;126(3):365-76. doi: 10.1309/UAXMW3428PGN9HJ3.

20. Ekanayaka A., Anderson J.T, Lucarotti M. E., et al. The isolated caecal patch lesion: a clinical, endoscopic and histopathological study. J Clin Pathol. 2020 Mar;73(3):121-125. doi: 10.1136/jclinpath-2019-206146.


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For citations:


Bikbavova G.R., Akhmedov V.A., Mozgovoy S.I., Telyatnikova L.I., Shmurygina E.A. Periappendicular changes in patients with ulcerative collitis: overview and clinical observation. Experimental and Clinical Gastroenterology. 2022;(9):298-302. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-205-9-298-302

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