Constipation syndrome in overweight patients
https://doi.org/10.31146/1682-8658-ecg-205-9-89-94
Abstract
Objective: the aim of our study was to study the relationship between constipation syndrome and obesity in gastroenterological patients. Materials and Methods: the study included 55 patients of the gastroenterology department of St. Petersburg State Budgetary Institution of Health “Elizavetinskaya Hospital”. Each patient was questioned according to the author’s questionnaire, which included the following indicators: age, height, body weight, body mass index (BMI), stool frequency (number a week), stool type according to the Bristol scale (1-7). Statistical processing was carried out using the SPSS8.0 software package. Results: The study revealed the following correlations: 1. BMI-age. BMI increases with age r=0.329 (p=0.014) 2. Stool frequency-age. With age, there is a decrease in the frequency of stools r= -0.651 (p<0.001) 3. Type of stool according to the Bristol scale-Age. With age, the type of stool shifts towards constipation r= -0.515 (p<0.001) 4. Type of stool according to the Bristol scale-BMI. With an increase n BMI, the stool shifts towards constipation r= -0.307 (p=0.023). Conclusions: according to the results of our study, we found the relationship between body mass index and constipation syndrome. It is necessary to pay special attention to patients with overweight in relation to complaints of constipation, as well as to made dynamic monitoring in order to prevent the development of colorectal cancer in patients with constipation.
About the Authors
Yu. P. Uspenskiy
St. Petersburg State Pediatric Medical University; Pavlov First St. Petersburg State Medical University
Russian Federation
Russian Federation
N. V. Baryshnikova
St. Petersburg State Pediatric Medical University; Pavlov First St. Petersburg State Medical University
Russian Federation
Russian Federation
Ya. V. Sousova
St. Petersburg State Pediatric Medical University; Science research institute
Russian Federation
Russian Federation
O. K. Kizimova
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
R. M. Niyazov
Pavlov First St. Petersburg State Medical University; Federal State Health Institution “Medical and Sanitary Unit of the Ministry of Internal Affairs of the Russian Federation for St. Petersburg and the Leningrad Region”
Russian Federation
Russian Federation
A. S. Ivanova
Saint Petersburg State Budgetary Healthcare Institution “City Clinical Hospital of the Righteous Martyr St. Elizaveta”
Russian Federation
Russian Federation
References
1. Uspenskiy Yu.P., Gorbacheva I. A., Gulunov Z. Kh., et al. [Metabolic syndrome: a textbook]. St. Petersburg. SPbGPMU Publ., 2020;76. (in Russ.) @@Успенский Ю. П., Горбачева И. А., Гулунов З. Х. и др. Метаболический синдром: учебное пособие. СПБГПМУ. Санкт-Петербург; 2020;76
2. Kyrou I., Randeva H. S., Tsigos C., et al. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000; PMID: 25905207.
3. Fominykh Yu.A., Gorbacheva I. A., Shemerovskiy K. A., et al. [Constipation problem and metabolic syndrome].Russian medical journal. 2018; 2: 7-1: 46-48. (in Russ.) @@Фоминых Ю. А., Горбачева И. А., Шемеровский К. А. и др. Проблема констипации и метаболический синдром. Русский медицинский журнал. Медицинское обозрение. 2018; 2: 7-1: 46-48.
4. Fominykh Yu.A. [Movement disorders and disorders of the intestinal microbiota as a gastroenterological cluster of metabolic syndrome: pathogenetic and clinical significance]. SPb, 2019, 66 P. (in Russ.). @@Фоминых Ю. А. Двигательные расстройства и нарушение микробиоты кишечника как гастроэнтерологический кластер метаболического синдрома: патогенетическое и клиническое значение. Автореферат диссертации на соискание ученой степени доктора медицинских наук. СПб, 2019; 66.
5. Dite P., Blaho M., Bojkova M., et al. Nonalcoholic Fatty Pancreas Disease: Clinical Consequences. Dig Dis. 2020;38(2):143-149. doi: 10.1159/000505366. PMID: 3186.
6. Lysov N.A., Osadchuk M. M., Osadchuk A. M. [Centrally mediated gastrointestinal pain disorders]. Bulletin of the medical institute “Reaviz”: rehabilitation, doctor and health. 2017; 1:37-39. (in Russ.) @@Лысов Н. А., Осадчук М. М., Осадчук А. М. Центрально-опосредованные желудочно-кишечные болевые расстройства. Вестник медицинского института «Реавиз»: реабилитация, врач и здоровье. 2017; 1:37-39.
7. Russian Gastroenterological Association. Association of Coloproctologists of Russia. [Clinical guidelines. Constipation]. 2020; 4. (in Russ.) @@Российская гастроэнтерологическая ассоциация. Ассоциация колопроктологов России. Клинические рекомендации. Запор. 2020; 4.
8. Forootan M., Bagheri N., Darvishi M. Chronic constipation: A review of literature. Medicine (Baltimore). 2018;97(20): e10631. doi: 10.1097/MD.0000000000010631. PMID: 29768326; PMCID: PMC5976340.
9. Birimoglu O. C., Bilgili N. Effect of abdominal massage on constipation and quality of life in older adults: A randomized controlled trial.Complement Ther Med. 2019;47:102219. doi: 10.1016/j.ctim.2019.102219. PMID: 31780015.
10. Wald A., Scarpignato C., Mueller-Lissner S., et al. A multinational survey of prevalence and patterns of laxative use among adults with self-defined constipation. Aliment Pharmacol Ther. 2008; 28(7):917-30. doi: 10.1111/j.1365-2036.2008.03806.x. PMID: 18644012.
11. Gray J. R. What is chronic constipation? Definition and diagnosis. Canadian Journal of Gastroenterology& Hepatology.2011; 25:7-10.
12. Minushkin O., Elizavetina G., Ardatskaya M., et al. [Chronic constipation: presentation, pathogenesis, diagnosis, new treatment options]. Vrach. 2012; 12: 77-82. (in Russ.). @@Минушкин О., Елизаветина Г., Ардатская М. и др. Хронический запор: представления, патогенез, диагностика, новые возможности лечения. Врач. 2012; 12: 77-82.
13. Bharucha A. E., Dorn S. D., Lembo A., et al. American Gastroenterological Association. American Gastroenterological Association medical position statement on constipation. Gastroenterology. 2013;144(1): 211-217.
14. Silveira E.A., Santos A. S.EAC, Ribeiro J. N., Noll M., Dos Santos Rodrigues AP, de Oliveira C. Prevalence of constipation in adults with obesity class II and III and associated factors. BMC Gastroenterol. 2021;21(1):217. doi: 10.1186/s12876-021-01806-5.
15. Wan Y., Zhang D., Xing T., et al. The impact of visceral obesity on chronic constipation, inflammation, immune function and cognitive function in patients with inflammatory bowel disease. Aging (Albany NY). 2021;13(5):6702-6711. doi: 10.18632/aging.202526. P
16. Macêdo MIP, Albuquerque MFM, Tahan S., et al. Is there any association between overweight, physical activity, fat and fiber intake with functional constipation in adolescents? Scand J Gastroenterol. 2020;55(4):414-420. doi: 10.1080/00365521.2020.1749878. PMID: 32320314.
17. Miron I., Dumitrascu D. L. Gastrointestinal motility disorders in obesity. Acta Endocrinol (Buchar). 2019;15(4):497-504. doi:10.4183/aeb.2019.497. PMID: 32377248; PMCID: PMC7200119.
18. Bertrand R.L., Senadheera S., Markus I., et al. A Western diet increases serotonin availability in rat small intestine. Endocrinology. 2011;152(1):36-47. doi: 10.1210/en.2010-0377. PMID: 21068163.
19. Huang H.H., Ting C. H., Syu Y. F. e al. Correlation between colonic secretion and colonic motility in rats: Role of ghrelin. World J Gastroenterol. 2016;22(46):10140-10147. doi: 10.3748/wjg.v22.i46.10140.
20. Halim M.A., Degerblad M., Sundbom M., et al. Inhibits Prandial Gastrointestinal Motility Through Myenteric Neuronal Mechanisms in Humans. J Clin Endocrinol Metab. 2018;103(2):575-585. doi: 10.1210/jc.2017-02006. PMID: 29177486.
21. Wisén O., Hellström P. M. Gastrointestinal motility in obesity. J Intern Med. 1995;237(4):411-8. doi: 10.1111/j.1365-2796.1995.tb01195.x. PMID: 7714465.
22. Alsheridah N., Akhtar S. Diet, obesity and colorectal carcinoma risk: results from a national cancer registry-based middle-eastern study. BMC Cancer. 2018;18(1):1227. doi: 10.1186/s12885-018-5132-9.
23. Sundbøll J., Thygesen S. K., Veres K., et al. Risk of cancer in patients with constipation. Clin Epidemiol. 2019;11:299-310. doi: 10.2147/CLEP.S205957.
24. Pare P. The approach to diagnosis and treatment of chronic constipation: suggestions for a general practitioner. Canadian Journal of Gastroenterology& Hepatology. 2011; 25: 36-40.
25. Turawa E.B., Musekiwa A., Rohwer A. C.Interventions for treating postpartum constipation. Cochrane Review. 2014.
26. Yurtdaş G., Acar-Tek N., Akbulut G., et al. Risk Factors for Constipation in Adults: A Cross-Sectional Study. J Am Coll Nutr. 2020;39(8):713-719. doi: 10.1080/07315724.2020.1727380. PMID: 32077808.
27. Anderson J.W., Baird P., Davis R. H. Jr., et al. Health benefits of dietary fiber. Nutr Rev. 2009;67(4):188-205. doi: 10.1111/j.1753-4887.2009.00189.x. PMID: 19335713.
28. Blake M.R., Raker J. M., Whelan K. Validity and reliability of the Bristol Stool Form Scale in healthy adults and patients with diarrhoea-predominant irritable bowel syndrome. Aliment Pharmacol Ther. 2016; 44(7):693-703. doi: 10.1111/apt.13746.
Review
For citations:
Uspenskiy Yu.P., Baryshnikova N.V., Sousova Ya.V., Kizimova O.K., Niyazov R.M., Ivanova A.S. Constipation syndrome in overweight patients. Experimental and Clinical Gastroenterology. 2022;(9):89-94. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-205-9-89-94
Views:
249
Email this article 